Registration Dossier
Registration Dossier
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EC number: 931-434-7 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50 (72h) = 17.89 mg/L (ISO 10253 (Water quality - Marine Algal Growth Inhibition Test with Skeletonema costatum and Phaeodactylum tricornutum))
Key value for chemical safety assessment
Additional information
One study is available on the short-term toxicity of Reaction products resulting from the esterification of Sorbitol with C8-18 (even) and C18unsaturated fatty acids in the ratio 1:1 (EC 931-434-7) to algae.
The key study conducted with Sorbitan laurate (CAS No. 1338-39-2) was performed according to the ISO 10253 (Water quality - Marine Algal Growth Inhibition Test with Skeletonema costatum and Phaeodactylum tricornutum) and GLP. The test organism Skeletonema costatum was exposed to the test substance in a static system for 72 hours, at the nominal test concentrations of 3.2, 10, 32, 100, 320 mg/L. The test solutions were prepared as water accommodated fractions (WAF). At the two lowest concentrations algal growth was stimulated by the test substance, but at the higher concentrations no growth was observed. The lack of a dose response relation rather indicates a physical effect caused by undissolved test material than a systemic toxic effect. An EC50 of 17.89 mg/L is reported. A NOEC is not reported, but as no adverse effect occurred up to 10 mg/L, the NOEC is 10 mg/L.
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