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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The EC50 for the toxicity of substances in the category to aquatic algae and cyanobacteria ranged from 7.71 - 16.5 mg/L. The results are above the water solubility for these substances.

Key value for chemical safety assessment

EC50 for freshwater algae:
7.71 mg/L

Additional information

No experimental data were available on the toxic effects of category members on algae. Due to the difficulty associated with aquatic toxicity testing with gases, QSAR calculations are considered suitable to estimate the effect concentration. ECOSAR Program v1.00 in EPI Suite v4.00 was used, which is acceptable with restrictions.The ECOSAR model is a reliable and appropriate QSAR model to apply to these substances as it is based on a related chemical dataset that calculates the toxicity of neutral organic hydrocarbons whose mode of action is non-polar narcosis.

QSAR calculations were conducted for substances which were representative of the carbon numbers of the members of the category (methane, ethane, propane, butane and isobutane). The 96 hour EC50 for algae is estimated to range from 7.71 to 16.5 mg/L in fresh water.