Magnesium hydrogenorthophosphate

Particle size distribution (Granulometry)

Link to relevant study record(s)

Reference

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Conducted according to suitable methodology and acceptable for assessment. This study is considered to be scientifically justified for use as a key study.

Qualifier:

no guideline followed

Principles of method if other than guideline:

The determination of particle size was made by a screening process with a specific mesh size in an air jet made by subpressure.

GLP compliance:

no

Type of method:

other: The determination of particle size was made by a screening process with a specific mesh size in an air jet made by subpressure.

Type of distribution:

volumetric distribution

Percentile:

D50

Remarks on result:

other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.

No.:

#1

Size:

< 45 µm

Distribution:

> 99 %

PROCEDURE:

Install test sieve, prescribed by the specification of the product. Weigh exactly 100 g of the sample into the weighing bottle and transfer it on to screen. Closed the lid and sieve for 3 mins in total. If fine materials stick together, they must be spread out with low pressure by using a brush during the sieve machine works.

Then close the lid again and sieve for the rest of the time. Weigh the oversize after 3 mins sieving.

 

 

Calculation:

 

Screen oversize (%) = residue (g) *100 /weight in g

Screen undersize (%) =100% - % screen oversize

Conclusions:

Particle size distribution indicates the substance is an inhalation risk (a significant proportion of the particles are present at < 100 µm).

Additional information

Particle size distribution indicates the substance is an inhalation risk (a significant proportion of the particles are present at < 100 µm).