Registration Dossier

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Remarks:
risk assessment
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Referenceopen allclose all

Reference Type:
other: risk assessment
Title:
Hydroquinone
Author:
ACGIH
Year:
1992
Bibliographic source:
American Conference of Governmental and Industrial Hygienists, Documentation of the Threshold Limit Values and Biological Exposure Indices. p. 789 - 792
Reference Type:
other: risk assessment
Title:
Hydroquinone
Author:
ACGIH
Year:
2001
Bibliographic source:
American Conference of Governmental and Industrial Hygienists, Documentation of the Threshold Limit Values and Biological Exposure Indices. p. 1-4
Reference Type:
review article or handbook
Title:
Cosmetic ingredient review. Final report on the safety assessment of hydroquinone and pyrocatechol.
Author:
CIR Expert Panel
Year:
1986
Bibliographic source:
J Am Coll Toxicol 5, 123 - 165
Reference Type:
review article or handbook
Title:
Toxicological aspects and health risks associated with hydroquinone in skin bleaching formula. (In Dutch with English abstract)
Author:
Kooyers TJ, Westerhof W
Year:
2004
Bibliographic source:
Ned Tijdschr Geneeskd 148, 768 - 771
Reference Type:
review article or handbook
Title:
Addendum to the final report on the safety assessment of Hydroquinone.
Author:
Zondlo MM
Year:
1994
Bibliographic source:
J Am Coll Toxicol 13, 167 - 230
Reference Type:
review article or handbook
Title:
The safety of hydroquinone.
Author:
Nordlund JJ, Grimes PE, Ortonne JP
Year:
2006
Bibliographic source:
J Eur Acad Dermatol Venereol 20, 781-787
Reference Type:
review article or handbook
Title:
Final amended safety assessment of hydroquinone as used in cosmetics.
Author:
Andersen FA, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW.
Year:
2010
Bibliographic source:
Int J Toxicol. 29(Suppl 6):274S-2787

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydroquinone
EC Number:
204-617-8
EC Name:
Hydroquinone
Cas Number:
123-31-9
Molecular formula:
C6H6O2
IUPAC Name:
hydroquinone

Results and discussion

Applicant's summary and conclusion