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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Remarks:
risk assessment
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Referenceopen allclose all

Reference Type:
other: risk assessment
Title:
Hydroquinone
Author:
ACGIH
Year:
1992
Bibliographic source:
American Conference of Governmental and Industrial Hygienists, Documentation of the Threshold Limit Values and Biological Exposure Indices. p. 789 - 792
Reference Type:
other: risk assessment
Title:
Hydroquinone
Author:
ACGIH
Year:
2001
Bibliographic source:
American Conference of Governmental and Industrial Hygienists, Documentation of the Threshold Limit Values and Biological Exposure Indices. p. 1-4
Reference Type:
review article or handbook
Title:
Cosmetic ingredient review. Final report on the safety assessment of hydroquinone and pyrocatechol.
Author:
CIR Expert Panel
Year:
1986
Bibliographic source:
J Am Coll Toxicol 5, 123 - 165
Reference Type:
review article or handbook
Title:
Toxicological aspects and health risks associated with hydroquinone in skin bleaching formula. (In Dutch with English abstract)
Author:
Kooyers TJ, Westerhof W
Year:
2004
Bibliographic source:
Ned Tijdschr Geneeskd 148, 768 - 771
Reference Type:
review article or handbook
Title:
Addendum to the final report on the safety assessment of Hydroquinone.
Author:
Zondlo MM
Year:
1994
Bibliographic source:
J Am Coll Toxicol 13, 167 - 230
Reference Type:
review article or handbook
Title:
The safety of hydroquinone.
Author:
Nordlund JJ, Grimes PE, Ortonne JP
Year:
2006
Bibliographic source:
J Eur Acad Dermatol Venereol 20, 781-787
Reference Type:
review article or handbook
Title:
Final amended safety assessment of hydroquinone as used in cosmetics.
Author:
Andersen FA, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW.
Year:
2010
Bibliographic source:
Int J Toxicol. 29(Suppl 6):274S-2787

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydroquinone
EC Number:
204-617-8
EC Name:
Hydroquinone
Cas Number:
123-31-9
Molecular formula:
C6H6O2
IUPAC Name:
hydroquinone

Results and discussion

Applicant's summary and conclusion