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EC number: 204-617-8 | CAS number: 123-31-9
The acute toxicity of hydroquinone to Daphnia magna was investigated in a study conducted equivalent or similar to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test) under semi-static conditions and under GLP. A 48 h EC50=0.134 mg/L based on measured initial concentration was determined.
Four studies dealing with the acute toxicity of hydroquinone to Daphnia are available; three studies with an exposure period of 48 hours and one study with 24 hours. The EC50 nvalues of the 48 hour tests ranged from 0.13 to 0.29 mg/L based on nominal or measured initial concentrations.
Only in one study the acute toxicity of hydroquinone to Daphnia magna was investigated equivalent to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test) under semi-static conditions and under GLP. The daphnids (20 animals/concentration) were exposed to measured concentration of 0 (control), 0.029, 0.043, 0.074, 0.11, and 0.18 mg/L for 48 h. The test substance concentrations were measured by HPLC/UV. The endpoint examined was immobilization. The 48 h NOEC, EC50, and EC100 were determined to be 0.029, 0.061, and 0.11 mg/L based on mean measured concentrations. As it has not been possible to discriminate between the effect of hydroquinone and its oxidation products the initial concentration is regarded as relevant concentration.
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