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EC number: 500-041-9 | CAS number: 25723-16-4 1 - 6.5 moles propoxylated
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2008-05-15 to 2008-06-12
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: 2b Guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- Version / remarks:
- It is not clearly specified which version was used.
- Qualifier:
- according to guideline
- Guideline:
- other: SS-EN ISO 7827:1996
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Remarks:
- To maintain aerobic conditions in the mediums air was bubbled from an air pump through a long glass tube which ended at the bottom of the flask.
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- The inoculum was prepared from activated sludge taken from Klagshamm waste water plant, Sweden. The activated sludge contained 5.9 g suspended solids /l.
- Duration of test (contact time):
- 35 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 78
- Sampling time:
- 28 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 80
- Sampling time:
- 28 d
- Details on results:
- The biodegradation test was prolongued to 35 days and after this time showed a plateau of approximately 89 % degradation.
The study report gives that the reference compound after 14 days was degraded more than 90 % without giving the reference substance identity. - Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- Biodegradation was determined according to OECD method 301A and is given as 78 and 80 % after 28 days, however, failing the 10 -day window. Thus, the substance is regarded as not ready biodegradable.
- Executive summary:
Biodegradation was determined according to OECD method 301A and is given as 78 % and 80 % after 28 days, however, failing the 10 -day window. Thus, the substance is regarded as not ready biodegradable.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study without detailed documentation.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Test temperature: 20 +/- 1 °C - Parameter:
- % degradation (O2 consumption)
- Value:
- 6
- Sampling time:
- 4 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 49
- Sampling time:
- 12 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 61
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 80
- Sampling time:
- 20 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 84
- Sampling time:
- 28 d
- Details on results:
- Kinetic of test substance (in %):
6 after 4 day(s)
49 after 12 day(s)
61 after 14 day(s)
80 after 20 day(s)
84 after 26 day(s) - Results with reference substance:
- 90% after 28 days (Anilin)
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Mineralisation of 84% was observed for TMP propoxylated in a manometric test, hence the test material was considered as readily biodegradable.
Referenceopen allclose all
Description of key information
The % biodegradability for the substance was 84% in 26 days and therefore it can be considered as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Biodegradation was determined according to OECD method 301A and in a manometric test. In the OECD301 A test, 78 % and 80 % biodegradation was observed after 28 days, however, failing the 10-day window. Thus, the substance is regarded as not ready biodegradable under the stringent conditions of the OECD 301 A. However, the manometric test is a more realistic simulation and in this test 84% biodegradation was observed. Therefore, the substance can be considered as readily biodegradable.
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