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EC number: 500-041-9
CAS number: 25723-16-4
1 - 6.5 moles propoxylated
The 96 hr LC50 to fish were reported as > 100 mg/l (nominal)(EU Method
C1 , Danio rerio).
The 48 hr EC50 to aquatic invertebrates were reported as >100
mg/L(nominal) (Daphnia magna).
The 21d-NOEC to aquatic invertebrates is ≥ 8.5 mg/L (nominal) for all
endpoints (nominal)(Daphnia magna).
72 hr ECr50 (Desmodesmus subspicatus) > = 100 mg/l.
72 hr NOEC (Desmodesmus subspicatus) > = 100 mg/l.
72 hr ECr50 (Pseudokirchnerella subcapitata) = 106 mg/l.
72 hr NOEC (Pseudokirchnerella subcapitata) = 31 mg/l.
3 hr (domestic sludge respiration rate inhibition) EC10 is >10,000 mgl/l
. No inhibition of respiration was observed.
No-Longer-Polymer (NLP) polyether polyols are
produced by the reaction of various starter molecules with propylene
oxide and/or ethylene oxide. These substances exhibit a remarkable
uniformity in the physical/chemical properties which influence their
fate and distribution in the environment. All NLP polyols have a full
acute aquatic ecotoxicity dataset and do not exhibit acute toxicity
below 100 mg/L. However, differentiation in chronic invertebrate
toxicity is apparent and is based on the alcohol- or amino- starter
molecules used to prepare these NLP polyols. A sub-grouping based on (i)
aliphatic alcohol and amine NLP polyols, (ii) EDA- (ethylenediamine)
based amino NLP polyols and (iii) o-TDA- (orthodiaminotoluene)
based aromatic NLP polyols is justified (ISOPA, 2010) and toxicity is
expected to be similar between substances within each of these
categories. It is considered appropriate to use ‘read-across’ of data of
structural analogues within each sub-grouping to fill data gaps for
chronic invertebrate toxicity and derive PNECs for endpoints based on
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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