Registration Dossier
Registration Dossier
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EC number: 203-906-6 | CAS number: 111-77-3
Endpoint summary
Administrative data
Description of key information
Additional information
If 2 -(2 -methoxyethoxy)ethanol is present in ambient air, it is expected to exist almost entirely in the vapour phase. This substance is not expected to absorb UV light in the environmentally significant range of >290 nm and is not therefore expected to undergo direct photolysis on sunlit soil surfaces, in the atmosphere or in aquatic environments. However, modelling predicts that it is likely to undergo indirect photolysis through hydroxyl radical reaction at a reasonably fast rate, with an estimated half life of 4.9 hours (0.41 days) at an OH concentration of 1.5million OH/cm3 and a 12 hour day). Based on its chemical structure, the substance is expected to be hydrolytically stable under normal environmental conditions.
Most of the test data available on biodegradation was generated according to international standard test guidelenes but the information available is not generally comprehensive and lacks some information on method details. However, the total set of information available is regarded as being sufficient to draw a conclusion on the degradation potential of 2 -(2 -methoxyethoxy)ethanol. Three guideline ready biodegradation studies are available to two different methods. Two were duplicate determinations to the same protocol. In a closed bottle test, the substance reached 68% degradation after 28 days but did not meet the 10 day window criteria of 60%. The modified sturm test (CO2 evolution) was repeated in duplicate. Both showed degradation of >75% after 28 days but only one met the 10 day window criteria. Since the average of these two results did meet the 10 day criteria, it can be concluded that 2 -(2 -methoxyethoxy)ethanol is readily biodegradable and does meet the 10 day window, although this is marginal. Ready biodegradability is also supported by QSAR modelling.
Based on the low logKow of this substance, the potential for bioaccumulation is predicted to be very low.
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