Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-906-6 | CAS number: 111-77-3
Endpoint summary
Administrative data
Description of key information
Additional information
A number of studies have been carried out using multiple species of fish, both fresh and salt water. One study in two species is sufficiently well reported to judge it as reliable and this can be used to derive the key parameters. All the other available experimental studies, whilst not individually robust, report data that is consistent with the key study and provide strong evidence that 2 -(2 -methoxyethoxy)ethanol is practically non-toxic to fish over the acute timeframe. The key parameter however is selected from a study for which the results are only currently available from a secondary source. This study is selected as it provides the lowest reported true LD50 reported in any of the studies that are available. This 96hr LC50 is 5700mg/l.
There is sufficient information available on the short term toxicity of 2 -(2 -methoxyethoxy)ethanol to Daphnia Magna from studies that were carried out to acceptable methods to be able to judge that the substance is of very low toxicity to invertebrates. No effects were seen at the highest concentrations tested in two of the studies and the third established an EC50 above these levels. The latter result is used for the key parameter EC50 for this taxonomic group.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
