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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Unsuitable test system

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1978
Report date:
1978
Reference Type:
secondary source
Title:
Unnamed
Year:
1987
Report date:
1978

Materials and methods

Principles of method if other than guideline:
The inhalation hazard test (IHT; synonymous to IRT, inhalation hazard test) was performed in principle as described in OECD Guideline 403 and in accordance to Smyth et al., Am.Ind.Hyg.Ass.J. 23,95-107 (1962). The aim of the test was to demonstrate the toxicity of an atmosphere saturated with vapors of the volatile components of the test substance at a temperature chosen for vapor generation (i.e. 20 °C for the present test substance).
The animals were exposed to the test substance for 7 hours (flow-through, 200 liters/hour).
GLP compliance:
no
Test type:
other: IHT
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Antimony nickel titanium rutile
EC Number:
701-459-6
Cas Number:
8007-18-9
Molecular formula:
Ni(x/3)Sb(2x/3)Ti(1-x)O2 0,1≤x≤0,3
IUPAC Name:
Antimony nickel titanium rutile
Test material form:
solid

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
whole body
Vehicle:
other: air
Duration of exposure:
7 h
Details on study design:
12 animals of unknown sex were exposed.

Results and discussion

Effect levels
Key result
Dose descriptor:
other: IHT
Remarks on result:
other: No mortality after 7 h exposition
Mortality:
not observed.
Clinical signs:
other: not observed.
Gross pathology:
nothing abnormal observed.

Applicant's summary and conclusion