Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-873-0 | CAS number: 127-95-7
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: In vitro
- Type of information:
- other: in vitro
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: OECD Guideline GLP study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 460: Guideline for testing of chemicals
- Principles of method if other than guideline:
- Fluorescin leakage test method for identifiying corrosive and severe irritants
- GLP compliance:
- yes
Test material
- Reference substance name:
- Potassium hydrogen oxalate
- EC Number:
- 204-873-0
- EC Name:
- Potassium hydrogen oxalate
- Cas Number:
- 127-95-7
- Molecular formula:
- C2H2O4.K
- IUPAC Name:
- potassium hydrogen oxalate
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- other: in vitro
- Time point:
- other: other
- Score:
- < 20
- Irritant / corrosive response data:
- The substance "potassium trihydrogen dioxalate" on the basis of the negative results cannot be classified as GHS cat1 in the experimental conditions performed. For this reason, it should be tested witha another validated in vitro or ex vivo ocular or skin protocol to assesss its eye irritation/corrosion potential following the sequential testing strategy for the acute eye irritation ab¡nd corrosion, outlined in the OECD TG 405 and EU Test Method B.5 (OECD, 21012; EU TRM B.5, 2008)
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
- Conclusions:
- The substance "potassium trihydrogen dioxalate" on the basis of the negative results cannot be classified as GHS cat1 in the experimental conditions performed. For this reason, it should be tested witha another validated in vitro or ex vivo ocular or skin protocol to assesss its eye irritation/corrosion potential following the sequential testing strategy for the acute eye irritation ab¡nd corrosion, outlined in the OECD TG 405 and EU Test Method B.5 (OECD, 21012; EU TRM B.5, 2008)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
