Registration Dossier
Registration Dossier
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EC number: 203-870-1 | CAS number: 111-44-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
Based on information provided in the database for dermal toxicity tests, BCEE has a low potential to irritate the skin.
Following application to rabbits' eyes, both pure grade BCEE and also its 10 % solution in propylene glycol caused moderate pain reactions, conjunctivitis and also damage to the cornea. However, all of the symptoms were reversible within 24 h.
Volunteers inhalatively exposed to concentrations of about 550 ppm were reported to have suffered after a short time period from unbearable severe irritation to the eyes and nose combined with cough, gag reflex and nausea. The irritation was still noticeable at 260 and 100 ppm but no longer at 35 ppm. The odour, characterized as repugnant, was still distinguished even at 35 ppm.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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