Registration Dossier
Registration Dossier
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EC number: 202-597-5 | CAS number: 97-63-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity to microorganisms: 30-min EC50 1000-1800 mg/L (activated sludge)
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate concentrations.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
Additional information
Activated sludge inhibition data (ISO 8192) are available for ethyl methacrylate and indicate a 30-min EC50 of 1000 -1800 mg/L. Further MAA and the lower alkyl methacrylate category members up to the BMA isomers show a low toxicity to micro-organisms while for 2-EHMA no toxicity has been observed up to and above the limit of solubility. See the following table:
Summary of effects on micro-organisms
|
Species |
Results |
Remarks |
Reference |
MAA |
Pseudomonas putida |
16h EC10= 100 mg/l |
16 h growth inhibition test, sensitive species |
Hanstveit, 1992 |
MMA |
Pseudomonas putida |
16h EC3= 100 mg/l |
16 h growth inhibition test, sensitive species |
Bringmann and Kühn, 1976, 1980ª |
MMA |
Activated sludge |
14 d NOEC = 100 mg/l |
Ready biodegradability test, OECD 310 C MITI (I) |
CITI, 1992 |
EMA |
Activated sludge |
30 min EC50= |
ISO8192 (OECD 209) respiration inhibition test |
Hund and Fabig, 1989 |
n-BMA |
Pseudomonas putida |
18h EC10≥ |
18 h growth inhibition test, sensitive species |
Fabig and Hund, 1988 |
i-BMA |
Pseudomonas fluorescens |
16h EC10> 281 mg/l* |
16 h growth inhibition test |
Rump(Fresenius), 1988 |
2-EHMA |
Activated sludge |
21 d NOEC = 100 mg/l |
OECD 301 C Modified MITI (I) Test |
CERI, 1998b |
* No growth inhibition with saturated solution
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