Registration Dossier
Registration Dossier
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EC number: 800-353-8 | CAS number: 1379524-06-7
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Adequacy of study:
- weight of evidence
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Publication data with only few information
Data source
Reference
- Reference Type:
- publication
- Title:
- Allergic contact Dermatitis from cocoamidopropyl betaine, cocamidoamine, 3-(Dimethylamino)propylamine, and oleamidopropyl dimethylamine : Co-reactions or cross- reactions?
- Author:
- Moreau L. and Sasseville D.
- Year:
- 2 004
- Bibliographic source:
- Dermatitis. 2004 Sep;15(3):146-9
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- case report
Test material
- Reference substance name:
- (9E)-N-[3-(dimethylamino)propyl]octadec-9-enamide
- EC Number:
- 800-353-8
- Cas Number:
- 1379524-06-7
- Molecular formula:
- C23H46N2O
- IUPAC Name:
- (9E)-N-[3-(dimethylamino)propyl]octadec-9-enamide
Constituent 1
Results and discussion
- Results of examinations:
- In this publication, the authors reported different cases of contact dermatitis caused by amido amines derivatives used in cosmetic products. Several experiments (patch-tests) found in literature and discussed in this paper confirm that the presence of 3-dimethylaminopropylamine (a feedstock found as an impurity) could be hypothesized to explain these allergic reactions.
Applicant's summary and conclusion
- Executive summary:
In this publication, the authors reported different cases of contact dermatitis caused by amido amines derivatives used in cosmetic products. Several experiments (patch-tests) found in literature and discussed in this paper confirm that the presence of 3-dimethylaminopropylamine (a feedstock found as an impurity) could be hypothesized to explain these allergic reactions.
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