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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Amides, C18-unsatd., N-[3-(dimethylamine)propyl]  were found to be toxic to green algae with an extrapolated ErC50 of 1.17 mg/L and an ErC10 of 0.32 mg/L, expressed as measured concentrations. 

Key value for chemical safety assessment

EC50 for freshwater algae:
1.17 mg/L
EC10 or NOEC for freshwater algae:
0.32 mg/L

Additional information

An algal growth inhibition test with Amides, C18-unsatd., N-[3-(dimethylamine)propyl] was conducted in accordance with OECD Test Guideline 201, and in compliance with the OECD principles of Good Laboratory Practice (Kean, 2013). Specific modifications to the guideline were that natural surface water was used for testing which was supplement with the recommended nutrients from the OECD algal medium at 50% concentration and NaHCO3 increased to 75 mg/L. The bulk approach was applied to the test methodology allowing the use of total aquatic concentrations for calculation of endpoints. The EC50 value of the reference compound, potassium dichromate, was in the range of 0.25-2.0 mg/L. The 72 hour ErC10 was calculated as 0.32 mg/L and the ErC50 > 0.96 mg/L (extrapolated value = 1.17 mg/L), expressed as measured initial values.