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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The LC50 for Danio rerio has been measured to be >100 mg/L after 96 h of exposure. The result is supported by a second study, in which the LC50 has been determined to be 206 mg/L.

Key value for chemical safety assessment

LC50 for freshwater fish:
206 mg/L

Additional information

The toxicity of N-butyl-2,2,6,6-tetramethylpiperidin-4-amine (N-butyl TAD) on fish has been studied in a key study, which has been performed according to EU Method C.1 (acute toxicity for fish) in compliance with GLP. In this study the effect of the different concentrations of the test substance on Brachydanio rerio (Danio rerio, Zebra fish) has been tested. No mortality occurred in this study and the LC50 has been determined to >100 mg/L after 96 h of exposure. In a supporting study, which is liminary reported, the toxicity of the test substance in Leuciscus idus melanotus (orfe) has been tested in a static, freshwater test according to DIN 38412 part 15. The LC50 is considered to be 206 mg/L after 48 h. Based on the results, fish is not considered to be the most sensitive aquatic species for n-butyl TAD.