Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Additional information

Overall these studies provide no evidence that 1,2-dichloropropane selectively targets the male or female reproductive systems or the developing embryo/fetus.


Lowest NOAEL values :

70 mg/kg bw/day for fertility

150 mg/kg bw for teratogenicity


Justification for classification or non-classification

Based on the results of the reported studies and taking into account the literature, 1,2-dichloropropane does not meet the classification criteria as toxic for reproduction.

Additional information