Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-152-2 | CAS number: 78-87-5
Neurotoxicity
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
No functional or histopathological changes were reported in brain or nervous tissue from rats given 1,2-dichloropropane at doses up to 200 mg/kg bw/d by gavage as part of a 13-week neurotoxicity study. The substance is therefore not considered a neurotoxin agent.
Justification for classification or non-classification
Based on the reported data,the substance is not considered a neurotoxin agent.
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