Registration Dossier

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well-documented publication

Data source

Reference
Reference Type:
publication
Title:
The hydrolysis of dimethylsulfate and diethylsulfate in water.
Author:
Robertson RE and Sugamori SE
Year:
1966
Bibliographic source:
Canadian Journal of Chemistry 44: 1728-1730

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
As described in: Roberston RE (1955): Reactions of arylsulphonic esters. III. On the hydrolysis of methyl -methylbenzenesulphonate. Canadian Journal of Chemistry 33: 1536-1543
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Dimethyl sulphate

The substance was redistilled under vacuum and the distillate repeatedly purified by partial freezing to give a product with m.p. -26.9 ° C.

Results and discussion

Dissipation DT50 of parent compound
pH:
7
Temp.:
25 °C
DT50:
1.2 h

Any other information on results incl. tables

RS-Freetext:
Empirical constants for the rate equation:
log10 k = A/T + B * log10 T + C

A = -7609.092
B = -22.1323
C = 76.5044
Temperature T (Kelvin)

Applicant's summary and conclusion