Registration Dossier
Registration Dossier
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EC number: 202-790-4 | CAS number: 99-82-1
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
Studies on gene mutations in bacterial systems (Ames, Hüls 1989 and Zeiger 1988) and mammalian cells (TK+/-,TC 2012) are available, where the test substance does not induce point mutations in presence and absence of metabolic activation. No chromosome aberrations were found in CHL cells in presence and absence of metabolic activation (TC 2012).
Endpoint Conclusion: No adverse effect observed (negative)
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
Short description of key information:
Studies on gene mutations in bacterial systems (Ames, Hüls 1989 and Zeiger 1988) and mammalian cells (TK+/-,TC 2012) are available, where the test substance does not induce point mutations in presence and absence of metabolic activation. No chromosome aberrations were found in CHL cells in presence and absence of metabolic activation (TC 2012).
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
The test substance does not need to be classified for mutagenicity.
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