Registration Dossier
Registration Dossier
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EC number: 942-139-8 | CAS number: 1170315-92-0
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Based on the read-across approach from the analogue OS 1600 which attained 1% biodegradation within 28 days, OS3600 was considered not readily biodegradable. A ready biodegradation test was also performed on MPKO, the hydrolytic product of OS3600. It was also considered to be not readily biodegradable (4-12% degradation within 28 days).
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Key study: Read-across approach from experimental data on the analogue substance OS1600:
The ready biodegradability test was performed in accordance with OECD Guideline 301B and EU Method C4 -C using the carbon dioxide (CO2) evolution test (modified Strum test) (GLP study). Sewage was exposed to 12 mg TOC/L (43 mg/2 litres) of test substance under aerobic conditions for 28 days. The relative degradation values based on CO2 consumption calculated from the measurements performed during the test period revealed no significant degradation (1% biodegradation within 28 days). Based on these results OS3600 was designated as not readily biodegradable.
Supporting study: The ready biodegradability test was performed with the analogue substance MPKO in accordance with OECD Guideline 301B and EU Method C4 -C using the carbon dioxide (CO2) evolution test (modified Strum test) (GLP study). Sewage was exposed to 12 mg TOC/L (40 mg/2 litres) of MPKO under aerobic conditions for 28 days. The relative degradation values based on CO2 consumption calculated from the measurements performed during the test period revealed 4 and 12% degradation within 28 days. The study was considered to be valid. In conclusion, the test item was designated as not readily biodegradable.
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