Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 222-182-2 | CAS number: 3380-34-5
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
28-d NOEC >= 100 mg/kg sediment
Key value for chemical safety assessment
Additional information
The sediment organism Chironomus sp. was exposed to Triclosan and the number of emerged animals as well as signs of intoxication of the animals was recorded during a test period of 28 days. The test was set up according to OECD guideline 218 with artificial sediment. A NOEC >= 100 mg/kg sediment was determined (Ciba Specialty Chemicals 2006).
Dussault (2008) performed toxicity tests with spiked sediment with Chironomus tentans and Hyalella azteca similar to US EPA guideline EPA/600/R-99/064. Deviating from the guideline a larger test vessel and a higher animal density were used. Due to analytical difficulties sediment concentrations were not verified, therefore effect values are based on nominal concentrations. Based on mortality a 10 -d LC50 of 397.6 mg/kg sediment for C. tentans and 198.8 mg/kg sediment for H. azteca were determined.
These studies confirm the results of the OECD 218 study by Ciba Specialty Chemcials (2006).
Two further studies were performed by Dussault (2008) with spiked-water exposing C. tentans and H. azteca for 10 -d under semi-static conditions. The studies were performed to the above mentioned US EPA guideline. The test concentrations were analytically verified. The 10 -d LC50 for C. tentans was 0.4 mg/L, the EC50 (growth) was 0.28 mg/L. For H. azteca, the 10 -d LC50 was 0.20 mg/L and the EC50 was 0.25 mg/L. Regarding the low environmental relevance of exposure only via water and the availability of the three spiked-sediment studies mentioned above, the results of these studies are not considered for the risk assessment.
The study by Ciba Specialty Chemicals (2006) was selected as key study since it is a long-term study and a NOEC was derived. In addition the study was performed according to GLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
