Registration Dossier
Registration Dossier
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EC number: 231-842-9 | CAS number: 7758-89-6
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: long-term
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Meets generally accepted scientific standards, well documented and acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- EFFECTS OF CADMIUM, COPPER, LEAD AND ZINC ON GROWTH, REPRODUCTION AND SURVIVAL OF THE EARTHWORM Eisenia fetida (SAVIGNY): ASSESSING THE ENVIRONMENTAL IMPACT OF POINT-SOURCE METAL CONTAMINATION IN TERRESTRIAL ECOSYSTEMS
- Author:
- Spurgeon et al.
- Year:
- 1 994
- Bibliographic source:
- Environmental Pollution Vol 84, pp.123-130
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- Deviations:
- yes
- Remarks:
- test duration 56 days
- GLP compliance:
- no
Test material
- Reference substance name:
- Cooper
- IUPAC Name:
- Cooper
Constituent 1
Test organisms
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- TEST ORGANISM
- Source: local vermicuturist
- Age at test initiation (mean and range, SD): at least 8 weeks
ACCLIMATION
- Acclimation period: 6 h
Study design
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 56 d
Test conditions
- Test temperature:
- 20 °C
- pH:
- 6.3 - 6.7
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per container (treatment): 10
- No. of replicates per treatment group: 4
- No. of replicates per control: 4
SOURCE AND PROPERTIES OF SUBSTRATE (if soil)
- Composition (if artificial substrate): artificial soil was prepared following OECD 207
OTHER TEST CONDITIONS
- Photoperiod: constant light - Nominal and measured concentrations:
- Nominal concentrations: 10, 40, 200, 1000 µg/g dry weight of soil
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- 683 other: µg/g
- Nominal / measured:
- nominal
- Basis for effect:
- mortality
- Duration:
- 56 d
- Dose descriptor:
- LC50
- Effect conc.:
- 555 other: µg/g
- Nominal / measured:
- nominal
- Basis for effect:
- mortality
- Duration:
- 56 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 210 other: µg/g
- Nominal / measured:
- nominal
- Basis for effect:
- mortality
- Duration:
- 56 d
- Dose descriptor:
- EC50
- Effect conc.:
- 53.3 other: µg/g
- Nominal / measured:
- nominal
- Basis for effect:
- reproduction
- Remarks on result:
- other: cocoon production
- Duration:
- 56 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 32 other: µg/g
- Nominal / measured:
- nominal
- Basis for effect:
- reproduction
- Remarks on result:
- other: cocoon production
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
