Registration Dossier
Registration Dossier
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EC number: 233-651-6 | CAS number: 10291-28-8
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The test item was assessed for its possible contact allergenic potential in a local lymph node assay performed according to OECD TG 429.
The animals did not show any clinical signs during the course of the study and no cases of mortality were observed.
In this study Stimulation Indices (S.I.) of 1.3, 1.8 and 1.1 were determined with the test item at concentrations of 5, 10 and 20% (w/v) in propylene glycol, respectively.
Migrated from Short description of key information:
Tested in the local lymh node assay the test item was not a skin sensitiser.
Justification for classification or non-classification
The substance was not a skin sensitiser in a study according to OECD TG 429, therefore classification for skin sensitisation is not required according to Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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