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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012-2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
column elution method
Water solubility:
< 1 µg/L
Temp.:
20
pH:
6.5 - 7
Remarks on result:
other: 2 values obtained at 2 different flow rates: 0.22 & 0.73 µg/L, mean value 0.48µg/L
Details on results:
See "Any other information on results incl. tables"

Water solubility results are presented in the following table (results in italics were considered as outlier values):

 

Sample

Time, hours

Test item concentration (µg/L)

Flow rate 25 mL/h

Flow rate 12.5 mL/h

8

22*

0.8

< LOQ

9

23

0.7

< LOQ

10

24

0.8

< LOQ

11

25

0.6

< LOQ

12

26

0.6

3.99

13

27

0.9

0.24

14

28

1.9

0.15

15

29

8.9

0.26

Mean values for each column

-

0.73

0.22

Mean value

 

0.48

*Precedent samples not available due to analytical issue

 

 

The mean values obtained at the 2 flow rates experiments are reported below:

 

Flow rate

Results

Column 1 (12.5 mL/h), mean value

0.22 µg/L

Column 2 (25 mL/h), mean value

0.73 µg/L

Mean Value

0.48 µg/L

 

Thus, as estimated by these results, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.

Conclusions:
Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.
Executive summary:

The water solubility of the test item COPPER DIBUTYLDITHIO CARBAMATE was assessed according to the OECD guideline 105. COPPER DIBUTYLDITHIO CARBAMATE appeared to be very difficult to test under the column method of OECD 105, as analysis revealed some erratic results due to test item uncontrolled particle release. Some results were thus considered as outlier values. The 30% variability a criterion of the guideline was thus not fulfilled; however some results can be used to estimate a water solubility value.

 

The mean values obtained at the 2 flow rates experiments are reported below:

 

Column 1 (12.5 mL/h), mean value: 0.22 µg/L

Column 2 (25 mL/h), mean value: 0.73 µg/L

Mean Value: 0.48 µg/L

 

Thus, as estimated by these results, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.

 

During the analysis, the temperature was 20 +/- 0.5 °C and the pH was 6.5 to 7.

Description of key information

Assessed according to OECD 105 guideline, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L. 

Key value for chemical safety assessment

Water solubility:
1 µg/L
at the temperature of:
20 °C

Additional information

The water solubility of the test item COPPER DIBUTYLDITHIO CARBAMATE was assessed according to the OECD guideline 105. COPPER DIBUTYLDITHIO CARBAMATE appeared to be very difficult to test under the column method of OECD 105, as analysis revealed some erratic results due to test item uncontrolled particle release. Some results were thus considered as outlier values. The 30% variability a criterion of the guideline was thus not fulfilled; however some results can be used to estimate a water solubility value.

 

The mean values obtained at the 2 flow rates experiments are reported below:

 

Column 1 (12.5 mL/h), mean value: 0.22 µg/L

Column 2 (25 mL/h), mean value: 0.73 µg/L

Mean Value: 0.48 µg/L

 

Thus, as estimated by these results, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.

 

During the analysis, the temperature was 20 +/- 0.5 °C and the pH was 6.5 to 7.