Registration Dossier
Registration Dossier
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EC number: 249-277-1 | CAS number: 28874-51-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96 Hour LC50 > 100 mg/L, NOEC 100 mg/L and LOEC > 100 mg/L, OCED 203, EU Method C.1 and EPA OPPTS 850.1075, Sipos (2013a).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 100 mg/L
Additional information
In the key study (Sipos, 2013a) the toxicity of the test material to fish was determined in an acute toxicity study performed under GLP conditions and in line with standardised guidelines. The study was assigned a reliability score of 1 in line with Klimisch (1997).
During the study Cyprinus carpio were exposed to the test material at a nominal concentration of 100 mg/L in a semi-static limit test, with an exposure period of 96 hours. Renewal was performed ever 24 hours throughout the exposure period. An untreated control was run concurrently for comparison. The concentration used in the definitive test was based on the results of two preliminary tests, in which no mortality was observed up to a maximum concentration of 100 mg/L. Analytical verification of the test solution concentration gave a geometric mean concentration of 99.07 mg/L, since the measured concentration deviated less than 20 % from the nominal biological results are based on the nominal concentration.
Under the conditions of the test no mortality or systemic signs of toxicity were observed in any of the treated fish. Based on these observations the NOEC was determined to be 100 mg/L, the LOEC > 100 mg/L, and the LC50 > 100 mg/L.
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