Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 249-277-1 | CAS number: 28874-51-3
Melting point / freezing point
Administrative data
Link to relevant study record(s)
Description of key information
188.7 ± 0.03 °C (461.9 K), OECD 102 and EU Method A. 1, Sárvári 2012a.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 188.7 °C
Additional information
The key study (Sárvári, 2012a) was performed under GLP conditions and in accordance with standardised guidelines. The study was assigned a reliability score of 1 in line with the principles for assessing data quality as defined by Klimisch (1997). Under the conditions of the test, the melting point of the test material was determined to be 188.7 ± 0.003 °C (461.9 K).
The supporting study (Butler, 2008) was performed using a read across substance, sodium 5-oxo-DL-prolinate, which is a racemic mixture of the D- and L- isomeric forms of the substance. Read-across is considered to be suitable based on the structural similarities between the read across substance (sodium 5-oxo-DL-prolinate) and the substance to be registered (sodium 5-oxo-L-prolinate), which is the L- isomer only. As such the difference in isomeric forms of the substance is unlikely to affect the physico-chemical properties. The study was conducted under GLP conditions and in accordance with standardised guidelines. The study was assigned a reliability score of 2 in line with the principles for assessing data quality as defined by Klimisch (1997). Under the conditions of the test, melting with decomposition was observed at approximately 337 °C (610K).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
