Registration Dossier

Diss Factsheets

Toxicological information

Sensitisation data (human)

Currently viewing:

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Secondary literature, peer-reviewed

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
Unnamed
Year:
1971
Report date:
1971
Reference Type:
secondary source
Title:
Report to RIFM.
Author:
Kligman AM
Year:
1971
Bibliographic source:
Cited in Anonymous (1975). RIFM Monographs on Cosmetic Ingredients. Isopulegol. Food Cosmet Toxicol 13: 823

Materials and methods

Type of sensitisation studied:
skin
Study type:
study with volunteers
Principles of method if other than guideline:
Maximization test according to
- Kligman AM (1966). The identification of contact allergens by human assay. III. The maximization test. A procedure for screening and rating contact sensitizers. J Invest Derm 47: 393.
- Kligman AM and Epstein W (1975). Updating the maximization test for identifying contact allergens, Contact Dermatitis 1: 231.
GLP compliance:
no
Remarks:
pre-GLP study

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopulegol
EC Number:
201-940-6
EC Name:
Isopulegol
Cas Number:
89-79-2
Molecular formula:
C10H18O
IUPAC Name:
isopulegol
Details on test material:
Isopulegol; no further data

Method

Type of population:
not specified
Route of administration:
dermal

Results and discussion

Results of examinations:
No sensitization reactions were observed.

Applicant's summary and conclusion

Categories Display