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EC number: 225-967-8 | CAS number: 5187-23-5
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 May to 12 June 2008
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- The inoculum was prepared from activated sludge taken from a waste water treatment plant (Klagshamn, Sweden). The activated sludge contained 5.9g/L suspended solids.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 68 mg/L
- Based on:
- test mat.
- Reference substance:
- acetic acid, sodium salt
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 4
- St. dev.:
- 0
- Sampling time:
- 14 d
- Remarks on result:
- other: Replicate 1: 4%, Replicate 2: 4%
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 84
- St. dev.:
- 19.79
- Sampling time:
- 21 d
- Remarks on result:
- other: Replicate 1: 70%, Replicate 2: 98%
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- ca. 93
- St. dev.:
- 1.41
- Sampling time:
- 28 d
- Remarks on result:
- other: Replicate 1: 94%, Replicate 2: 92%
- Validity criteria fulfilled:
- yes
- Remarks:
- OECD 301, Readily biodegradable if, 1. DOC removal >70% within 28d 2. 10d window was achieved and ended within 28d
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The substance cyclic trimethylolpropane formal (CTF) is readily biodegradable.
- Executive summary:
The biodegradability of cyclic trimethylolpropane formal (CTF) was determined according to OECD guideline 301A (DOC Die away test). The amount of biodegradation observed comprised 4% after 14 days but increased to 84% after 21 days. CTF can therefore be classified as readily biodegradable and passing the 10 day window.
Reference
Description of key information
One key study is presented. This study demonstrates that the test substance Cyclic trimethylolpropane formal (CTF) has been found to the readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The test substance 5-ethyl-1,3-dioxane-5-methanol has been found to the readily biodegradable with >90% removal after 28 days in both the key and supporting studies. As such removal in the environment is expected to be rapid and complete.
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