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EC number: 217-617-8 | CAS number: 1912-24-9
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 14 june 1993 to 13 October 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- other: EPA OPP guideline 63-11
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Atrazine
- EC Number:
- 217-617-8
- EC Name:
- Atrazine
- Cas Number:
- 1912-24-9
- Molecular formula:
- C8H14ClN5
- IUPAC Name:
- 6-chloro-N2-ethyl-N4-(propan-2-yl)-1,3,5-triazine-2,4-diamine
- Details on test material:
- Atrazine (pure grades)
Batch number 744
Purity 99.5%
Expiry: Stable until at least January 2995
Storage 4°C
Appaerance: white powder
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.59
- Temp.:
- 20 °C
- pH:
- 7.31 - 7.51
- Details on results:
- calibration data show ed a slop of 449576, an intercept of 7301 and a correlation coefficient of 0.99860. Thus, the response of the instrument was shown to be linear over the calibration range used.
The assessment of the reproducibility of the analysis was performed doing seven injection of a calibration solution that produced a mean area of 1200714, with a standard deviation of 6580.9 and a coefficient of variation of 5%.
Standard deviation of individual P values about the mean is 14.034
Applicant's summary and conclusion
- Conclusions:
- the partition coefficient ( n-octanol/water) of atrazine (pure) has been determined as:
Log P = 2.59 at 20°C
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