Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 14 June 1993 to 13 October 1993
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report Date:
1994

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
Qualifier:
according to
Guideline:
other: EPA OPP guidelines 63-8
Deviations:
yes
Remarks:
the water solubility test was performed in distilled water only and at 20°C only
Principles of method if other than guideline:
The PKa value is so low (1.56) that the water solubility test was performed in distilled water only and not using buffers at 3 pH values (4, 7, 9) since the atrazine molecule would be in the same form at all these pH's and solubility would not be effected. In addition the preliminary work indicated a water solubility of 4.04x10^-2 g/l at 30°C and hence a solubility temperature dependence of less than 3% per °C compared to the 20°C result. Therefore the test was performed at 20°C only and not at two other temperatures at least 10°C above and 20°C below of the test temperature.
GLP compliance:
yes
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Atrazine (pure grades)
Batch number 744
Purity 99.5%
Expiry: Stable until at least January 2995
Storage 4°C
Appaerance: white powder

Results and discussion

Water solubility
Water solubility:
0.032 g/L
Temp.:
20 °C
pH:
8.07 - 8.46
Details on results:
The water solubility results (uncorrected for purity) rangs from 0.03115 to 0.03351 g/L and pH from 8.07 to 8.46.
The mean water solubility was determined as 0.03193 g/L (corrected for purity) with an associated standard deviation of 8.75 x 10^-4 g/L

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)