Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 14 June 1993 to 13 October 1993
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report date:
1994

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
other: EPA OPP guidelines 63-8
Deviations:
yes
Remarks:
the water solubility test was performed in distilled water only and at 20°C only
Principles of method if other than guideline:
The PKa value is so low (1.56) that the water solubility test was performed in distilled water only and not using buffers at 3 pH values (4, 7, 9) since the atrazine molecule would be in the same form at all these pH's and solubility would not be effected. In addition the preliminary work indicated a water solubility of 4.04x10^-2 g/l at 30°C and hence a solubility temperature dependence of less than 3% per °C compared to the 20°C result. Therefore the test was performed at 20°C only and not at two other temperatures at least 10°C above and 20°C below of the test temperature.
GLP compliance:
yes
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Atrazine
EC Number:
217-617-8
EC Name:
Atrazine
Cas Number:
1912-24-9
Molecular formula:
C8H14ClN5
IUPAC Name:
6-chloro-N2-ethyl-N4-(propan-2-yl)-1,3,5-triazine-2,4-diamine
Details on test material:
Atrazine (pure grades)
Batch number 744
Purity 99.5%
Expiry: Stable until at least January 2995
Storage 4°C
Appaerance: white powder

Results and discussion

Water solubility
Water solubility:
0.032 g/L
Temp.:
20 °C
pH:
8.07 - 8.46
Details on results:
The water solubility results (uncorrected for purity) rangs from 0.03115 to 0.03351 g/L and pH from 8.07 to 8.46.
The mean water solubility was determined as 0.03193 g/L (corrected for purity) with an associated standard deviation of 8.75 x 10^-4 g/L

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)