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Key value for chemical safety assessment

Additional information

Mutagenic activity of the test item was investigated in Salmonella typhimurium strains TA 98, TA 100, TA 1535 and TA 1537 with and without metabolic activation (induced rat liver S9) at concentrations of 4, 20, 100, 500, 2500 and 5000 µg/plate.

The test item did not reveal any mutagenic activity under the conditions tested (plate incorporation assay).

Short description of key information:
Not mutagenic in the bacterial reverse mutation assay in concentrations up to 5000 µg/plate (S. typhimurium strains TA 98, TA 100, TA 1535, TA 1537).

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

In a bacterial reverse mutation assay the test substance was not mutagenic. Therefore the test substance has not to be classified for mutagenicity according to the criteria set in Regulation (EC) No 1272/2008.