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Long-term toxicity to aquatic invertebrates

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Description of key information

Chronic toxicity to Daphnia results are read across from polysulfides, di-tert-dodecyl.

No biologically significant effects were observed over the course of the study at the limit test concentration.

Key value for chemical safety assessment

Additional information

Chronic toxicity to Daphnia results are read across from polysulfides, di-tert-dodecyl. For further information please see the read across justification attached in the IUCLID robust study summary.

Migchielsen (2016) assessed chronic toxicity of polysulfide, di-tert-dodecyl in Daphnia magna. The study followed standard OECD guidelines (OECD 211) and used a single test concentration slightly above the saturation limit of the test item (nominally 1.3 µg/L), using acetone as a solvent. This equated to an average measured concentration of 0.79 µg/L in theDaphniastudy (measured using UPLC-MS/MS). Effects on reproduction were assessed over 21 days in a semi-static study. No biologically significant effects were observed over the course of the study at the limit test concentration.

The study followed standard guidelines and used test methods suitable for the poorly soluble test item, it is therefore considered to be reliable without restrictions.