Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

Currently viewing:

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1964
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from review article (report on chlorophenols - systematic review and critical evaluation of relevant data).

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Unnamed
Year:
1991
Reference Type:
publication
Title:
No information
Year:
1964
Bibliographic source:
Gigiena i Sanitariya (GISAAA). English translation: Hygiene and Sanitation, USSR (HYSAAV) , Vol. 29(10), Pg. 37 (1964)

Materials and methods

Principles of method if other than guideline:
The study was conducted before a guideline was available. No further data are on-hand.
GLP compliance:
no
Remarks:
prior to GLP
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chlorophenol
EC Number:
203-402-6
EC Name:
4-chlorophenol
Cas Number:
106-48-9
Molecular formula:
C6H5ClO
IUPAC Name:
4-chlorophenol

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Analytical verification of test atmosphere concentrations:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
11 mg/m³ air
Based on:
test mat.

Applicant's summary and conclusion