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Diss Factsheets
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EC number: 278-934-5 | CAS number: 78521-39-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Vehicle:
- no
- Test organisms (species):
- Poecilia reticulata
- Details on test organisms:
- TEST ORGANISM
- Source: fish farmer Branislav Settey, SKLOCHEM-AGROEKOLAB, Zvolen
- Length at study initiation: 2.0 +- 1.0 cm
- Feeding during test: none
ACCLIMATION
- Acclimation period: held in laboratory 12 days before test - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Hardness:
- 151 mg/L (CaCO3)
- Test temperature:
- 21.1°C - 22.3°C
- pH:
- 8.13 - 8.22
- Dissolved oxygen:
- 63.75 - 82.61% of saturation
- Nominal and measured concentrations:
- 4200.0, 4326.0, 4455.8, 4589.0, 4727.1, 4869.0 mg/L (nominal concentrations, initial)
measured concentrations: max. -10.00% of nominal - Details on test conditions:
- TEST SYSTEM
- Type: closed
- Materia: glass or other chemically inert material
- Aeration: not during test
- No. of organisms per concentration: 7
- Biomass loading rate: max. 1.0 g fish/L
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: ISO 6341 test water
- Chlorine:< 10 µg/L
- Intervals of water quality measurement: oxygen and pH measured daily
OTHER TEST CONDITIONS
- Adjustment of pH: yes, 1 N NaOH to pH 8.2
- Photoperiod: 16 h light / 8 h dark:
EFFECT PARAMETERS MEASURED:
mortality recorded after 24, 48, 72 and 96 hours
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 1.03
- Range finding study: yes - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4 693 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4 436 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Results with reference substance (positive control):
- - Mortality: 96h-EC50 = 115.40 mg/L (mean of 3 determinations)
- Sublethal observations / clinical signs:
Mortality data:
Nominal concentration
[mg/L]Mortality 48 h
[%]Mortality 96 h
[%]4200.0
0
0
4326.0
14
43
4455.8
14
57
4589.5
29
71
4727.1
43
86
4869.0
86
100
Control
0
0
- Validity criteria fulfilled:
- yes
- Executive summary:
The acute toxicity of ASC Plus to the fish Poecilia reticulata was tested according to OECD guideline 203. The test resulted in a 96h-LC50 of 4436 mg/L.
Reference
Description of key information
The acute toxicity of ASC Plus to the fish Poecilia reticulata was tested according to OECD guideline 203.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 4 436 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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