Diamminediisocyanatozinc

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

until 1986-11-13

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Remarks:

only summary and parts of the in general well-documented study report available

Qualifier:

according to guideline

Guideline:

EU Method A.8 (Partition Coefficient - Shake Flask Method)

Version / remarks:

Preliminary test A.6.1.6.2 was used to obtain the apparent solubility of the test item in octanol saturated with water and in water saturated with octanol.

Deviations:

not specified

GLP compliance:

not specified

Type of method:

flask method

Partition coefficient type:

octanol-water

Analytical method:

not specified

Key result

Type:

log Pow

Temp.:

20 °C

Remarks on result:

not determinable

Remarks:

Apparent insolubility in octanol and instability in water preclude measurement of the partition coefficint for the test item. Apllication of a standard test for solubility gave apparent solubility of ca. 10exp(-2) g/l of the test item in water saturated with octanol and <<10exp(-2) g/l for the test item in in octanol saturated with water at room temperature. Although the test item appered to flocculate and disperse on dilution with water the test material seemed to agglomerate in octanol with no change on dilution and storage.

Conclusions:

Only summary and parts of the in general well-documented study report available, but given data indicate that the study was performed properly and the results are reliable.

Executive summary:

Apparent insolubility in octanol and instability in water preclude measurement of the partition coefficint for the test item. Apllication of a standard test for solubility gave apparent solubility of ca. 10exp(-2) g/l of the test item in water saturated with octanol and <<10exp(-2) g/l for the test item in in octanol saturated with water at room temperature.

Although the test item appered to flocculate and disperse on dilution with water the test material seemed to agglomerate in octanol with no change on dilution and storage.

Description of key information

Apparent insolubility in octanol and instability in water preclude measurement of the partition coefficient for the test item. Application of a standard test for solubility gave apparent solubility of ca. 10exp(-2) g/l of the test item in water saturated with octanol and <<10exp(-2) g/l for the test item in in octanol saturated with water at room temperature.

Although the test item appered to flocculate and disperse on dilution with water the test material seemed to agglomerate in octanol with no change on dilution and storage.