Registration Dossier
Registration Dossier
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EC number: 619-946-6 | CAS number: 890707-29-6
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics, other
- Type of information:
- not specified
- Adequacy of study:
- supporting study
- Study period:
- 17.08.2011
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other: Toxicokinetic Assessment
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
- GLP compliance:
- not specified
Results and discussion
Applicant's summary and conclusion
- Executive summary:
The study presented provide an overview of the toxicological profile of IN-L8E22 and an analysis of the toxicokinetic behaviour of the substance.
Based on molecular weight and its physical chemical properties particularly water solubility and logPow, IN-L8E22 will most likely be absorbed following exposure. If bioavailable, the substance will most likely distribute through intracellular compartments. Metabolism will include phase I and phase II metabolising enzymes. No toxic activation was observed. Excretion will occur most likely via urine and to a lesser extent via faeces. Bioaccumulation is not likely.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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