Registration Dossier
Registration Dossier
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EC number: 619-946-6 | CAS number: 890707-29-6
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- June 2009 - August 2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Reference substance name:
- 2-Amino-5-cyano-N,3-dimethylbenzamide
- Cas Number:
- 890707-29-6
- Molecular formula:
- C10H11N3O
- IUPAC Name:
- 2-Amino-5-cyano-N,3-dimethylbenzamide
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- 0.17 g/L
- Temp.:
- 20 °C
- pH:
- >= 5.8 - <= 5.95
Any other information on results incl. tables
Table 1: Solubility results - definitive test
| Average solubility (g/L) | |||
| Sampling hour | MilliQ water | Average | Std. |
| 24 | 0.17 | 0.17 | 0.011 |
| 48 | 0.16 | ||
| 72 | 0.16 | ||
Applicant's summary and conclusion
- Conclusions:
- The solubility of the test substance in Milli-Q water was determined to be 0.17 g/L at 20 ± 0.5°C.
- Executive summary:
The present study was conducted to determine the water solubility of the test substance, according to OECD Guideline105, EEC A.6 and OPPTS 830.7840.
The solubility of the test substance was studied in Milli-Q water incubated under laboratory condition at 30 ± 1°C and measured at 20 ± 0.5°C. Solubility was studied with saturated solutions of the test substance in Milli-Q water by shake flask method. The samples were analysed for test item concentration by high performance liquid chromatography.
The solubility of the test substance in Milli-Q water was determined to be 0.17 g/L at 20 ± 0.5°C.
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