Registration Dossier
Registration Dossier
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EC number: 265-805-3 | CAS number: 65520-42-5
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- short-term repeated dose toxicity: oral
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Adipic acid diesters category. See attached report.
Data source
Materials and methods
Test material
- Reference substance name:
- Bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl] adipate
- EC Number:
- 265-807-4
- EC Name:
- Bis[2-[2-(2-butoxyethoxy)ethoxy]ethyl] adipate
- Cas Number:
- 65520-46-9
- Molecular formula:
- C26H50O10
- IUPAC Name:
- bis{2-[2-(2-butoxyethoxy)ethoxy]ethyl} adipate
- Test material form:
- other: liquid
Constituent 1
Results and discussion
Effect levels
- Key result
- Dose descriptor:
- NOAEL
- Effect level:
- 100 mg/kg bw/day (nominal)
- Basis for effect level:
- other: not specified
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
- Conclusions:
- According to the category read-across approach, the lowest NOAEL from a 28-day oral repeated dose toxicy study with rats (OECD TG 407) available among category members is 100 mg/kg bw/day.
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