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EC number: 202-409-1 | CAS number: 95-31-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
TBBS is not readily biodegradable with a biodegradability of 0% observed in 28 days (Bayer, 1991). The described main degradation products of TBBS are also not readily biodegradable.
According to the REACh Annex IX the degradation behaviour of TBBS should be further investigated in a simulation study in the most relevant compartment. The registrant intends to further elucidate the biodegradation in the compartment soil, as TBBS can be considered between moderately sorptive and highly or strongly (ad)sorptive based on its inherent properties logPow = 3.36 (exp. Duslo, 2007) and logKoc between 2.69 and 4.06 (calc. Currenta 2016).
TBBS is a member of the sulphenamide category and the category member N-cyclohexylbenzothiazole-2-sulphenamide (CBS, CAS 95-33-0, EC 202-411-2) exhibits an even higher adsorption potential (logKOW = 5.02, logKOC = 3.33 – 4.13) with a longer hydrolytic half-life t1/2 = 12.5 h. Based on these properties, a simulation study on ultimate degradation in soil (OECD 307) is planned on CBS to provide the necessary information on degradation potential of this highly adsorptive, hydrolytically unstable substance as detailed in ECHA Guidance R.7c (2017, p.29) to appropriately design a potential test on bioaccumulation.
If the OECD 307 on CBS results in not P, it will serve as proof of degradation of TBBS in soil following the above rationale (ECHA Guidance R.7b p. 233), as based on its physicochemical properties (higher adsorption, slower hydrolysis) CBS will serve as a worst case scenario.
If the OECD 307 on CBS will show that the more adsorptive substance must be classified as P, the registrant will consider further investigation on the degradation of TBBS in soil, to assess the remaining uncertainties from that result.
As a conclusion, a biodegradation simulation study in soil (OECD 307) is proposed by the registrant on CBS which appears to be more suitable to describe the degradation behaviour of CBS in the environment and might serve as a worst case scenario for the category member TBBS.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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