Registration Dossier
Registration Dossier
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EC number: 256-350-1 | CAS number: 48076-38-6
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The adsorption coefficient of tetradecyl acrylate was estimated using KOCWIN v2.00 embedded in EPI Suite v4.11 of EPA’s Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC). The program is a screening level tool and estimates the log Koc adsorption coefficient using a Molecular Connectivity Index (MCI). Icosyl acrylate has a molecular weight of 352.61 g/mol and therefore fits the applicability domain of this model. A log Koc of 6.42 was derived for the test item.
Key value for chemical safety assessment
Additional information
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met. Furthermore according to Article 25 of the same Regulation testing on vertebrate animals shall be undertaken only as a last resort.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of tetradecyl acrylate (Q)SAR results were used for assessment of Adsorption.The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Further experimental studies are not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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