Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 256-350-1 | CAS number: 48076-38-6
Endpoint summary
Administrative data
Description of key information
According to REACH Regulation 1907/2006/EC, Annex IX section 9.3.2 column 2 a study for bioaccumulation in aquatic species, preferably fish need not be conducted if no direct or indirect exposure to the aquatic environment is expected. At production sites, the esters are handled in closed systems for polymerisation. Diffuse releases into the environment from residual monomers in the polymeric products are not of concern due to the extremely low vapour pressure of the substances. Direct and indirect exposure of the substances in the category to water is highly unlikely. Thus no test is required. The bioaccumulation potential of the substances was calculated using the EPISUITE (v.4.11) software.
Result on bioaccumulation in water/sediment
Ester |
Alcohol Moiety Chain length |
Method |
BCF* |
logBCF* |
Reference |
Dodecyl acrylate [2156-97-0] |
C12 |
calcutated |
293.3 |
2.467 |
EPISUITE |
Tetradecyl acrylate [21643-42-5] |
C14 |
calculated |
190.0 |
2.279 |
EPISUITE |
Hexadecyl acrylate [13402-02-3] |
C16 |
calcutated |
50.0 |
1.699 |
EPISUITE |
Octadecyl acrylate [4813-57-4] |
C18 |
calcutated |
10.95/323.6** |
1.040 |
EPISUITE |
Icosyl acrylate [48076-38-6] |
C20 |
calcutated |
2.906/106.8** |
0.463 |
EPISUITE |
Docosyl acrylate [18299-85-9] |
C22 |
caclcluated |
1.316/35.27** |
0.119 |
EPISUITE |
*(including biotransformation rate, mid trophic)
**based on log Pow
Conclusion
Long-chain acrylates are not expected to accumulate in the body, based on their metabolic elimination, this is supported by calculation with EPISUITE.
Additional information
The bioaccumulation potential of the 2 -Propenoic acid, icosyl esters was calculated to be 2.91/(106.8) L/kg or log BCF = 0.463 using the EPA Epiwin (v.4.11) software. Furthermore, direct and indirect exposure of the test item to water and soil is highly unlikely. According to Annex XIII a substance does not fulfils the Bioaccumulation criterion (B-) when the bioconcentration factor (BCF) is lower than 2000, therefore a test for bioaccumulation: aquatic/sediment does not need to be conducted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
