Registration Dossier
Registration Dossier
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EC number: 203-026-2 | CAS number: 102-36-3
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: well documented and scientifically acceptable
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 984
- Report date:
- 1984
Materials and methods
- Type of study / information:
- hematotoxicity
- Principles of method if other than guideline:
- single oral application per gavage of 100 mg/kg bw of substance to 1 male and 50 mg/kg bw to 1 female cat. Haemogram and clinicl signs were examinated.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3,4-dichlorophenyl isocyanate
- EC Number:
- 203-026-2
- EC Name:
- 3,4-dichlorophenyl isocyanate
- Cas Number:
- 102-36-3
- Molecular formula:
- C7H3Cl2NO
- IUPAC Name:
- 1,2-dichloro-4-isocyanatobenzene
- Details on test material:
- purity: > 98 %
Constituent 1
Results and discussion
Any other information on results incl. tables
As clinical symptoms decreased activity, salivation and diarrhoea were seen. The substance had no influence to the haemogram.
Applicant's summary and conclusion
- Executive summary:
single oral application per gavage of 100 mg/kg bw of substance to 1 male and 50 mg/kg bw to 1 female cat. Haemogram and clinicl signs were examinated.
As clinical symptoms decreased activity, salivation and diarrhoea were seen. The substance had no influence to the haemogram.
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