Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 252-471-9 | CAS number: 35265-04-4
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21‑day NOEC was determined to be 0.32 mg test item/L for the reproduction.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.32 mg/L
Additional information
The influence of 2-(sec-butylamino)ethanol to Daphnia magna in a semi-static reproduction test has been investigated through OECD Guideline 211 and according to GLP requirements (Kuhl, 2011). The mortality of adults and the number of young Daphnia were determined after 21 days of exposure to several concentrations (3.2, 1.0, 0.32, 0.1 and 0.032 mg test item/L). In the freshly prepared test media 108 % of the nominal test concentrations were found (all concentrations above the NOEC). In the aged test media 96 % of the nominal values were determined (all concentrations above the NOEC). Under the test conditions the test item was sufficiently stable during the test medium renewal periods of 48 and 72 hours. Therefore, all reported results are related to nominal concentrations of the test item. The 21‑day NOEC was determined to be 0.32 mg test item/L for the reproduction and 0.32 mg test item/Lfor the survival of the adult test animals, respectively. The EC50 for the reproduction was 0.904 mg test item/L. All the validity criteria were fulfilled.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
