Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: limited but acceptable documented study report which meets basic scientific principles

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1975
Report Date:
1975

Materials and methods

Principles of method if other than guideline:
Method: other acute dermal toxicity study
GLP compliance:
no
Test type:
other: acute dermal toxicity study

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Bantex

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
male/female

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
corn oil
Duration of exposure:
24 h
Doses:
7940
No. of animals per sex per dose:
2
Control animals:
no

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 7 940 mg/kg bw
Based on:
test mat.
Remarks on result:
other: clinical signs like reduced appetite and activity

Any other information on results incl. tables

Mortality: no death occured during the study (0/2)

Clinical signs observed: reduced appetite and activity (two to four days)

Gross autopsy (survivors): viscera appeared normal

Applicant's summary and conclusion