Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: publication does not give sufficient experimental details

Data source

Reference
Reference Type:
publication
Title:
Bioavailability of rubber accelerators in rubber gloves and patch test reactivity
Author:
Knudsen, B., B.; et al.
Year:
2000
Bibliographic source:
Dermatol. Beruf Umwelt 48, Heft 4, 127-133

Materials and methods

Type of sensitisation studied:
skin
Study type:
other: study with dermatitis patients
Principles of method if other than guideline:
other: patch test with dermatitis patients
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Zinc di(benzothiazol-2-yl) disulphide
EC Number:
205-840-3
EC Name:
Zinc di(benzothiazol-2-yl) disulphide
Cas Number:
155-04-4
Molecular formula:
C7H5NS2.1/2Zn
IUPAC Name:
zinc 1,3-benzothiazole-2-thiolate
Details on test material:
zinc-mercaptobenzothiazole

Method

Type of population:
general
Route of administration:
dermal

Results and discussion

Results of examinations:
8/25 patients with postive patch-test reactions

Applicant's summary and conclusion