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EC number: 204-435-9 | CAS number: 120-92-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Seyfried ( 2007) was selected as key study, since conducted according to standardised guidelines (OECD 301F) and GLP.
In this study,Cyclopentanone was investigated for its ready biodegradability in a manometric respirometry test over 28 days.
At 28-day exposure period, the mean biodegradation of Cyclopentanone amounted to 102%.
The pass level for ready biodegradability, i.e. biodegradation of at least 60% of the ThOD in a 10-day window within the 28-day period of the test, was reached.
Consequently, Cyclopentanone was found to be completely biodegradable under the test conditions within 28 days.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Two experimental studies were available and were taken into account for the assessment.
The first one (Seyfried, 2007), dealed with the ready biodegradability and was selected as key study.
In this study, Cyclopentanone was investigated for its ready biodegradability in a manometric respirometry test over 28 days according to OECD Guideline for Testing of Chemicals No. 301 F.
The percent biodegradation of the test item was calculated based on the theoretical oxygen demand (ThOD) of 2.47 mg O2/mg test item.
In the toxicity control, containing both Cyclopentanone and the reference item sodium benzoate, Cyclopentanone had no inhibitory effect on the activity of activated sludge microorganisms at the testedconcentrationof 100 mg/L.
In the procedure controls, the reference item sodium benzoate was degraded by anaverage of 93%by Exposure Day 14, and reached an average biodegradationof 98%by the end of the test (Day 28), thus confirming suitability of the activated sludge.
The results are considered valid since the following criteria are met:
The oxygen demand of the inoculum control (medium and inoculum) was 2-10 mg O2/L within 28 days (criterion: normally 20-30 mg O2/L but not greater than 60 mg O2/L).
The degradation rates of the two test flasks containing the test item, test water and inoculum deviated by 1% at the end of the test (criterion: not more than 20% deviation at the time the plateau is reached, at the end of the test or at the end of the 10-day window).
The percentage degradation of the reference item reached the level for ready biodegradability (at least 60% of ThOD in a 10-day window) by Day 4 (criterion: at least 60% of ThOD in a 10-day window by Day 14 for the reference item).
At 28-day exposure period, the mean biodegradation of Cyclopentanone amounted to 102%.
Moreover, the pass level for ready biodegradability, i.e. biodegradation of at least 60% of the ThOD in a 10-day window within the 28-day period of the test, was reached.
Consequently, Cyclopentanone (distilled) was found to be completely biodegradable under the test conditions within 28 days.
Therefore, Cyclopentanone can be classified as readily biodegradable under the test conditions.
The other available study (Pitter, 1976) was selected as supporting study and also concluded that Cyclopentanone was inherently biodegradable.
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