Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

No bioaccumulation potential

Key value for chemical safety assessment

Bioaccumulation potential:
no bioaccumulation potential

Additional information

No data available on this substance. However, there are relevant published data on sulphates and sulphites.

Sulphites, which are commonly used as preservatives, are continuously formed in the body during the metabolism of sulphur-containing amino acids. Sulphite is rapidly oxidized to sulphate ion by sulphite oxidase in the liver (Vural Kucukatay et al, and Sun YP et al). Four rats given oral doses of sodium metabisulfite as a 0.2% solution eliminated 55% of the sulphur as sulphate in the urine within the first four hours (Bhagat & Locket 1960). A rapid and quantified elimination of sulphites as sulphate was also observed in man and dog (Rost 1933).