Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
265-185-4
CAS no.:
64742-82-1
Index number:
Molecular formula:
C22H40
SMILES:
CCCCCCC.CC1CCCCC1.CCC1=CC=CC=C1
InChI:
InChI=1S/C8H10.C7H14.C7H16/c1-2-8-6-4-3-5-7-8;1-7-5-3-2-4-6-7;1-3-5-7-6-4-2/h3-7H,2H2,1H3;7H,2-6H2,1H3;3-7H2,1-2H3 AuxInfo=1/0/N:22,21,18,17,19,16,20,15;14,11,10,12,9,13,8;1,7,2,6,3,5,4/E:(4,5)(6,7);(3,4)(5,6);(1,2)(3,4)(5,6)/rA:22CCCCCCCCCCCCCCCCCCCCCC/rB:s1;s2;s3;s4;s5;s6;;s8;s9;s10;s11;s8s12;s8;;d-15;s16;d-17;s18;s15d-19;s15;s21;/rC:-4.0389,.309,0;-2.6828,-.4416,0;-1.359,.3251,0;-.0018,-.4254,0;1.3704,.3333,0;2.6941,-.4336,0;4.018,.3333,0;10.5269,.9407,0;11.3223,-.3761,0;10.5213,-1.7049,0;8.998,-1.7049,0;8.1978,-.3761,0;9.0146,.9295,0;11.2833,2.2919,0;.4736,-7.4143,0;1.2695,-8.7434,0;.4736,-10.0723,0;-1.026,-10.0723,0;-1.8505,-8.7576,0;-1.026,-7.4429,0;1.2338,-6.0854,0;.4521,-4.7848,0;
Type of substance:
UVCB
Origin:
Petroleum product
Registered compositions:
24
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (ATP05) approved by the European Union, this substance may be fatal if swallowed and enters airways, may cause genetic defects, may cause cancer and causes damage to organs through prolonged or repeated exposure.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance is toxic to aquatic life with long lasting effects, is an extremely flammable liquid and vapour, is suspected of damaging fertility or the unborn child, causes skin irritation and may cause drowsiness or dizziness.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is a flammable liquid and vapour.

Breakdown of all 2136 C&L notifications submitted to ECHA

Asp. Tox. 1 H304 Harmonised Classification
Carc. 1B H350 Harmonised Classification
Muta. 1B H340 Harmonised Classification
STOT SE 3 H336
Aquatic Chronic 2 H411
Flam. Liq. 3 H226
STOT RE 1 H372 Harmonised Classification
Skin Irrit. 2 H315
Flam. Liq. 2 H225
Repr. 2 H361
Aquatic Chronic 3 H412
Flam. Liq. 1 H224
Aquatic Chronic 1 H411
STOT SE 3 H335
Eye Irrit. 2 H319
https://echa.europa.eu/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification.

Properties of concern

  • C
Officially recognised in the EU as Carcinogenic (Harmonised C&L).
  • C
There is broad agreement in that a majority of data submitters agree this substance is Carcinogenic (100% of REACH registrations).
  • M
Officially recognised in the EU as Mutagenic (Harmonised C&L).
  • M
There is broad agreement in that a majority of data submitters agree this substance is Mutagenic (100% of REACH registrations).

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 23 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 000 - 10 000 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels, air care products, anti-freeze products, coating products, lubricants and greases, washing & cleaning products and welding & soldering products.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), indoor use as processing aid and outdoor use as processing aid.

This substance is used in the following activities or processes at workplace: production of mixtures or articles by tabletting, compression, extrusion or pelletisation and the low energy manipulation of substances bound in materials or articles.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and as processing aid.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring and in materials as fuel sources, with limited exposure to unburned product to be expected.

Other release to the environment of this substance is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

This substance is used in the following products: lubricants and greases and coating products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: formulation of mixtures and/or re-packaging. This substance is used for the manufacture of: chemicals and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance, as processing aid, of substances in closed systems with minimal release, formulation of mixtures, in the production of articles, as processing aid and for thermoplastic manufacture.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as processing aid, formulation of mixtures, formulation in materials, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: do not breathe the dust, fume, gas, mist, vapours or spray; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; obtain special instructions before use; avoid release to the environment; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. Do not induce vomiting.

Storage statements

Store this substance in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Alsanea Chemical Trading SA, 1, rue Aristide Briand 1263 Luxembourg Luxembourg
  • api raffineria di Ancona S.p.A., via Flaminia 685 60015 Falconara Marittima (AN) Italy
  • COMPANÍA ESPAÑOLA DE PETRÓLEOS, S.A.U. (CEPSA), Torre Cepsa, Paseo de la Castellana 259A 28046 Madrid Spain
  • Envigo Research Limited 101, Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom
  • Equinor ASA, Forusbeen 50 N-4035 Stavanger Norway
  • Glencore Energy UK Ltd, 50 Berkeley Street W1J 8HD London United Kingdom
  • GRUPA LOTOS S.A., ul. Elblaska 135 80-718 Gdańsk pomorskie Poland
  • Gunvor Petroleum Rotterdam B.V., Moezelweg 255 3198 LS Europoort Netherlands
  • ISAB S.r.l., ex S.s. 114 km 146 96010 Priolo Gargallo (SR) Sicily Italy
  • ITELYUM Purification S.r.l., Via S. Intini n. 2 27015 Landriano (PV) Italy
  • momaja s.r.o, Karolinska 650/1 186 00 Prague 8 Czech Republic
  • Neste Oyj, Keilaranta 21 FI-02150 Espoo Finland
  • ORLEN Południe S.A., Fabryczna 22 32-540 Trzebinia Malopolska Poland
  • Petroineos Trading Limited, 11th Floor, The Adelphi, 1-11 John Adam Street, WC2N 6HT London United Kingdom
  • Petróleos de Portugal - Petrogal, S.A., Rua Tomás da Fonseca, Torres de Lisboa 1600-209 Lisboa Portugal
  • Public Company ORLEN Lietuva, JUODEIKIAI LT-89467 MAZEIKIAI TELSIAI Lithuania
  • Raffineria di Milazzo S.C.p.A., Contrada Mangiavacca 98057 Milazzo (ME) Italy
  • Ramboll Environment & Health GmbH, Werinherstraße 79 Gebäude 32a 81541 München Germany
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland
  • Repsol Petroleo, S.A., Calle Mendez Alvaro, 44 28045 Madrid Madrid Spain
  • Shell Trading International Ltd, Shell Centre SE1 7NA London United Kingdom
  • Shell Trading Rotterdam B. V., Weena 70 3012 CM Rotterdam Netherlands
  • TOTAL EUROPEAN TRADING, 2 Place Jean Millier La Défense 6 92400 Courbevoie France
  • PARAMO, a.s., Přerovská 560 53006 Pardubice Czech Republic
  • PETROBRAS EUROPE LIMITED., 9th Floor, 1 Angel Court EC2R 7HJ London United Kingdom
  • PETROBRAS GLOBAL TRADING BV - PGT BV, Weena 762 - 9th Floor, First Rotterdam 3014 DA Rotterdam Netherlands
  • Total Lindsey Oil Refinery ltd, Eastfield Road DN40 3LW North Lincolnshire United Kingdom

Substance names and other identifiers

[A complex combination of hydrocarbons obtained from a catalytic hydrodesulfurization process. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90 °C to 230 °C (194 °F to 446 °F).]
A complex combination of hydrocarbons obtained from a catalytic hydrodesulfurization process. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 230°C (194°F to 446°F).
C&L Inventory
Low boiling point hydrogen treated naphtha
A complex combination of hydrocarbons obtained from a catalytic hydrodesulfurization process. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 230°C (194°F to 446°F).
C&L Inventory
Naphtha (petroleum), hydrodesulfurized heavy
EC Inventory, REACH pre-registration
naphtha (petroleum), hydrodesulphurized heavy
A complex combination of hydrocarbons obtained from a catalytic hydrodesulfurization process. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 230°C (194°F to 446°F).
C&L Inventory
(Keerulise koostisega süsivesinike segu, mis saadakse katalüütilisest hüdrodesulfuriseerimisprotsessist. Koosneb süsivesinikest, mille süsiniku aatomite arv on valdavalt vahemikus C7 kuni C12, ning on keemistemperatuuriga umbes 90°C kuni 230 °C.) (et)
C&L Inventory
(Složeni sastav ugljikovodika dobiven postupkom katalitičke hidrodesulfurizacije. Sastoji se od ugljikovodika koji imaju broj ugljikovih atoma pretežito u području od C7 do C12 i vriju u području približno od 90 °C do 230 °C.) (hr)
C&L Inventory
[Kompleks blanding av hydrokarboner dannet ved katalytisk hydrogenavsvovling. Består av hydrokarboner, hovedsakelig C7 til C12, med omtrentlig kokepunktsintervall fra 90 °C til 230 °C (194 °F til 446 °F).] (no)
C&L Inventory
[Kompleksna kombinacija ogljikovodikov dobljena v katalitskem procesu razžvepljevanja z vodikom. Sestoji iz ogljikovodikov s številom ogljikovih atomov pretežno v območju med C7 in C12 ter ima vrelišče v območju približno med 90 °C in 230 °C.] (sl)
C&L Inventory
[komplexe Kombination von Kohlenwasserstoffen, erhalten durch katalytische Hydrodesulfurierung; besteht aus Kohlenwasserstoffen mit Kohlenstoffzahlen überwiegend im Bereich von C7 bis C12 mit einem Siedebereich von etwa 90 °C bis 230 °C] (de)
C&L Inventory
[Komplexná zmes uhľovodíkov získavaná katalytickým hydrogenačným odsírením. Pozostáva z uhľovodíkov s počtom atómov uhlíka prevažne v rozmedzí od C7 do C12. Má teplotu varu v rozmedzí približne od 90 °C do 230 °C.] (sk)
C&L Inventory
[O combinaţie complexă de hidrocarburi obţinute prin procesul de hidro-desulfurare catalitică. Constă în principal în hidrocarburi al căror număr de atomi de carbon variază în principal între C7 şi C12, al căror punct de fierbere este cuprins între aproximativ 90°C şi 230°C (194°F şi 446°F).] (ro)
C&L Inventory
[Ogļūdeņražu savienojumu komplekss, kas iegūts katalītiskās hidrodesulfurizācijas procesā. Sastāv no ogļūdeņražiem ar oglekļa atomu skaitu pārsvarā no C7 līdz C12, aptuvenā viršanas temperatūra no 90°C līdz 230°C (194°F līdz 46°F).] (lv)
C&L Inventory
[Složitá směs uhlovodíků získaná katalytickým hydrogenačním odsířením. Je složena z uhlovodíků s počtem uhlíkových atomů převážně v rozmezí C7 až C12 a s rozmezím teplot varu přibližně 90 °C až 230 °C.] (cs)
C&L Inventory
[Sudėtinis angliavandenilių mišinys, gaunamas vykdant katalizinį hidrodesulfuravimą. Jį sudaro angliavandeniliai, turintys anglies atomų skaičių daugiausia nuo C7 iki C12, ir kurių virimo temperatūra maždaug nuo 90 °C iki 230 °C (nuo 194 °F iki 446 °F).] (lt)
C&L Inventory
[Szénhidrogének komplex elegye, melyet katalitikus hidrogénes kéntelenítésből nyernek. Olyan szénhidrogénekből áll, melyek szénatomszáma főleg a C7-C12 tartományban van. Forrásponttartománya kb. 90°C-tól 230°C-ig (194°F-től 446°F-ig) terjed.] (hu)
C&L Inventory
[Πολύπλοκος συνδυασμός υδρογονανθράκων που λαμβάνεται από την καταλυτική υδρογονοαποθείωση. Συνίσταται από υδρογονάνθρακες με αριθμό ατόμων άνθρακα κυρίως μεταξύ C7 και C12 που αποστάζουν μεταξύ 90 °C και 230 °C περίπου.] (el)
C&L Inventory
[Комплексна комбинация от въглеводороди, получена при каталитичен хидродесулфуриращ процес. Състои се от въглеводороди с брой на въглеродните атоми основно в интервала от C7 до C12 включително, и с температура на кипене приблизително в интервала от 90°C до 230°C (194°F до 446°F).] (bg)
C&L Inventory
Alacsony forráspontú hidrogénnel kezelt benzin (hu)
C&L Inventory
Benzin (nafta), hidrodesulfuriziran teški (hr)
C&L Inventory
Benzin (nyersolaj), hidrogénnel kéntelenített nehéz (hu)
C&L Inventory
Benzyna ciężka hydroodsiarczona (ropa naftowa) (pl)
C&L Inventory
Benzínová frakce (ropná), hydrogenačně odsířená, těžká (cs)
C&L Inventory
combinación compleja de hidrocarburos obtenida de un proceso de hidrodesulfuración catalítica; compuesta de hidrocarburos con un número de carbonos en su mayor parte dentro del intervalo de C7 a C12 y con un intervalo de ebullición aproximado de 90 °C a 230 °C (es)
C&L Inventory
Combinaison complexe d'hydrocarbures obtenue par un procédé d'hydrodésulfuration catalytique. Se compose d'hydrocarbures dont le nombre de carbones se situe en majorité dans la gamme C7-C12 et dont le point d'ébullition est compris approximativement entre 90°C et 230°C. (fr)
C&L Inventory
Combinazione complessa di idrocarburi ottenuta da un processo di idrodesolforazione catalitica. È costituita da idrocarburi con numero di atomi di carbonio prevalentemente nell'intervallo C7-12 e punto di ebollizione nell'intervallo 90 °C - 230 °C ca. (da 194°F a 446°F). (it)
C&L Inventory
Combinação complexa de hidrocarbonetos proveniente de um processo de hidrodessulfuração catalítica. É constituída por hidrocarbonetos com número de átomos de carbono predominantemente na gama C7 a C12 e destilação no intervalo aproximado de 90 °C a 230 °C. (pt)
C&L Inventory
Een complexe verzameling koolwaterstoffen, verkregen uit een katalytisch waterstofontzwavelingsproces. Bestaat uit koolwaterstoffen, overwegend C7 tot en met C12, met een kooktraject van ongeveer 90°C tot 230°C. (nl)
C&L Inventory
En sammensat blanding af carbonhydrider opnået ved en katalytisk hydroafsvovlningsproces. Den består af carbonhydrider, overvejende C7 til og med C12, med kogeinterval omtrent fra 90 °C til 230 °C (194 ºF til 446 ºF). (da)
C&L Inventory
Fracţia nafta (petrol), fracţiunea grea hidrodesulfurată (mt)
C&L Inventory
Gehydrogeneerde nafta met laag kookpunt (nl)
C&L Inventory
Hidrogenēts ligroīns ar zemu viršanas temperatūru (lv)
C&L Inventory
hydrogenovaný ťažký benzín s nízkou teplotou varu (sk)
C&L Inventory
Komplex blandning av kolväten, erhållen genom katalytisk väteavsvavling. Består av kolväten, främst C7 till C12, med ungefärligt kokpunktsintervall från 90 °C till 230 °C. (sv)
C&L Inventory
Lavtkogende hydrogeneret nafta (da)
C&L Inventory
lavtkokende hydrogenbehandlet nafta (no)
C&L Inventory
Ligroīns (nafta), hidrodesulfurizēts, smagais (lv)
C&L Inventory
Lågkokande vätebehandlad nafta (sv)
C&L Inventory
Madala keemispunktiga hüdrogeenitud raskbensiin (et)
C&L Inventory
Matalalla kiehuva vetykäsitelty teollisuusbensiini (fi)
C&L Inventory
Monimutkainen seos hiilivetyjä, saatu katalyyttisestä prosessista rikin poistamiseksi vedyn avulla. Koostuu hiilivedyistä, joiden hiililuvut ovat pääasiassa välillä C7:sta C12:ään ja jotka kiehuvat likimäärin välillä 90°C:sta 230°C:een (194°F:sta 446°F:iin). (fi)
C&L Inventory
Nafta (aardolie), waterstofontzwavelde zware (nl)
C&L Inventory
nafta (petroleum), hydrogenavsvovlet tung (no)
C&L Inventory
Nafta (petroleum), väteavsvavlad tung (sv)
C&L Inventory
nafta (petrolio), pesante idrodesolforata (it)
C&L Inventory
nafta (petróleo), fracción pesada hidrodesulfurada (es)
C&L Inventory
Nafta (petróleo), hidrodessulfurada, pesada (pt)
C&L Inventory
nafta (zemeljsko olje), težka razžvepljena z vodikom (sl)
C&L Inventory
Nafta cu punct de fierbere scăzut tratată cu hidrogen (mt)
C&L Inventory
Nafta de baixo ponto de ebulição tratada com hidrogénio (pt)
C&L Inventory
nafta di hydrotreating con basso punto di ebollizione (it)
C&L Inventory
nafta tratada con hidrógeno de bajo punto de ebullición (es)
C&L Inventory
naphta hydrotraité à point d'ébullition bas (fr)
C&L Inventory
Naphta lourd (pétrole), hydrodésulfuré (fr)
C&L Inventory
Naphtha (Erdöl), hydrodesulfuriert, schwer (de)
C&L Inventory
naphtha (råolie), hydroafsvovlet tung (da)
C&L Inventory
Naphtha, wasserstoffbehandelt, niedrigsiedend (de)
C&L Inventory
Nisko-vrijući hidroobrađen benzin (hr)
C&L Inventory
Niskowrząca frakcja naftowa obrabiana wodorem (pl)
C&L Inventory
Nízkovroucí hydrogenovaná benzínová frakce (cs)
C&L Inventory
O combinaţie complexă de hidrocarburi obţinute prin procesul de hidro-desulfurare catalitică. Constă în principal în hidrocarburi al căror număr de atomi de carbon variază în principal între C7 şi C12, al căror punct de fierbere este cuprins între aproximativ 90°C şi 230°C (194°F şi 446°F). (mt)
C&L Inventory
Pirminis benzinas (nafta), hidronusierintas sunkusis (lt)
C&L Inventory
Raskbensiin (nafta), hüdrodesulfureeritud, raske (et)
C&L Inventory
Teollisuusbensiini (maaöljy), rikitön raskas (fi)
C&L Inventory
z vodikom obdelana nafta z nizko temperaturo vrelišča (sl)
C&L Inventory
Złożona mieszanina węglowodorów otrzymywana z procesu katalitycznego hydroodsiarczania. Składa się z węglowodorów o liczbie atomów węgla głównie w zakresie od C7 do C12, wrzących w zakresie temp. od ok. 90°C do 230°C. (pl)
C&L Inventory
ťažký benzín (ropný), ťažká frakcia, hydrogenačne odsírený (sk)
C&L Inventory
Žematemperatūris hidrintas pirminis benzinas (lt)
C&L Inventory
Νάφθα χαμηλού σημείου ζέσεως από υδρογονοεπεξεργασία (el)
C&L Inventory
νάφθαΝάφθα (πετρελαίου), βαριά υδρογονοαποθειωμένη (el)
C&L Inventory
Нискооктанов бензин (нефт), хидродесулфуриран-тежък (bg)
C&L Inventory
Обработен с водород нискооктанов бензин с ниска температура на кипене (bg)
C&L Inventory
(petroleum), hydrodesulfurized heavy
C&L Inventory
[A complex combination of hydrocarbons obtained from a catalytic hydrodesulfurization process. It consists of hydrocarbons having carbon numbers predominantly in ...
C&L Inventory
A complex combination of hydrocarbons obtained from a catalytic hydrodesulfurization process. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 230°C (194°F to 446°F).
C&L Inventory
ethylbenzene; heptane; methylcyclohexane
Registration dossier, Other
Fatty acids, tall-oil
C&L Inventory
n/a
C&L Inventory
nafta
C&L Inventory
Nafta pesante idrodesolforata
C&L Inventory
Naphta (petroleum)
C&L Inventory
Naphta (petroleum), Hydrosulphurized heavy
C&L Inventory
naphta lourds hydrodésulfurés
C&L Inventory
naphtha
C&L Inventory
Naphtha (petroleum
C&L Inventory
Naphtha (petroleum) hydrodesulfurized heavy
C&L Inventory
Naphtha (petroleum), hydrodesulfurized
C&L Inventory
Naphtha (petroleum), hydrodesulfurized heavy - A complex combination of hydrocarbons obtained from a catalytic hydrodesulfurization process. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90 degrees C to 230 degrees C (194 degrees F to 446 degrees F).
C&L Inventory
Naphtha (petroleum), hydrodesulfurized heavy / Naphtha (petroleum), hydrodesulfurized heavy
Registration dossier
NAPHTHA (PETROLEUM), HYDRODESULFURIZED HEAVY, CONTAINS less 0.1% BENZENE
C&L Inventory
Naphtha (petroleum), hydrodesulfurized heavy; low boiling point hydrogen treated naphtha
C&L Inventory
Naphtha (petroleum), hydrodesulfurized heavy; Low boiling point hydrogen treated naphtha;
C&L Inventory
Naphtha (petroleum), Hydrosulfurized heacy
C&L Inventory
Naphtha (petroleum), isomerization
Registration dossier
Naphtha, (petroleum), hydrodesulfurized heavy
C&L Inventory
NAPHTHA, PETROLEUM, HYDRODESULFURIZED HEAVY
C&L Inventory
Naphtha,(petroleum) hydrodesulfurised heavy
C&L Inventory
Naptha (petroleum), hydrodesulfurized heavy
C&L Inventory
Naptha heavy hydrodesulfurized
C&L Inventory
Not applicable
C&L Inventory
Not available
C&L Inventory
Reaction mass of 90622-57-4 and 90622-58-5
C&L Inventory
Testbenzin 145/200
C&L Inventory
White Spirit
C&L Inventory, Registration dossier
AGUARRAS
Registration dossier
AGUARRAS (Terebentina)
Registration dossier
AGUARRAS INTERMEDIARIA
Registration dossier
Turpetine
Registration dossier
64742-82-1
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other
649-330-00-2
Index number
C&L Inventory

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 2 studies processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [2]
C Form
Other (100%) [2]
C Substance type
Petroleum product (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 4 studies submitted
  • 2 studies processed
R Boiling point
-20 - 260 °C @ 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 2 studies submitted
  • 2 studies processed
R Relative density
0.62 - 0.88 @ 15 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 2 studies submitted
  • 2 studies processed
R Vapour pressure
240 kPa @ 37.8 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Partition coefficient

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 2 studies submitted
  • 2 studies processed
R Flash point
-40 °C [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 8 studies submitted
  • 4 studies processed
R Autoflammability / self-ignition
280 - 470 °C @ 101.3 - 101.325 kPa [4]

Type of Study provided
Studies with data
Key study 2 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 2 studies submitted
  • 2 studies processed
C Interpretation of results
Extremely flammable (100%) [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Flammability
Extremely flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
C Summaries
  • 2 summaries submitted
  • 2 summaries processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 4 studies submitted
  • 2 studies processed
R kinematic viscosity (in mm²/s)
1 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 14 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 12
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 93.02 % [1]
R Water 5.83 % [1]
R Soil 0.34 % [1]
R Sediment 0.81 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 2 summaries submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No data available: testing technically not feasible (1)
Intermittent releases (freshwater) No data available: testing technically not feasible (1)
Marine water No data available: testing technically not feasible (1)
Intermittent releases (marine water) No data available: testing technically not feasible (1)
Sewage treatment plant (STP) No data available: testing technically not feasible (1)
Sediment (freshwater) No data available: testing technically not feasible (1)
Sediment (marine water) No data available: testing technically not feasible (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil No data available: testing technically not feasible (1)
Hazard for Predators
Secondary poisoning Insufficient hazard data available (further information necessary) (1)

Short–term toxicity to fish

Study results
  • 32 studies submitted
  • 4 studies processed
P/RResults
LL50 (4 days) 8.2 - 10 mg/L [4]

Type of Study provided
Studies with data
Key study 4
Supporting study 28
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 4 studies submitted
  • 2 studies processed
P/RResults
EL50 (21 days) 10 mg/L [2]
NOELR (21 days) 2.6 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 24 studies submitted
  • 2 studies processed
P/RResults
EL50 (48 h) 4.5 mg/L [2]
NOELR (48 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 22
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 6 studies submitted
  • 2 studies processed
P/RResults
NOELR (21 days) 2.6 - 16 mg/L [4]
EL50 (21 days) 10 - 40 mg/L [4]

Type of Study provided
Studies with data
Key study 2
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 32 studies submitted
  • 2 studies processed
P/RResults
EL50 (4 days) 3.7 mg/L [2]
EL50 (72 h) 3.1 mg/L [2]
NOELR (72 h) 500 µg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 30
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
EC50 (40 h) 15.41 mg/L [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: High hazard (no threshold derived)
Acute /short term: Low hazard (no threshold derived)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 2
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 87 studies submitted
  • 2 studies processed
P/RResults
LD50 5 000 mg/kg bw (rat) [2]
M/CInterpretations of results
Not classified [2]

Type of Study provided
oral
Studies with data
Key study 1 1
Supporting study 45 40
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 79 studies submitted
  • 4 studies processed
M/CInterpretations of results
Not classified [4]

inhalation
Studies with data
Key study 3 1
Supporting study 36 39
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 89 studies submitted
  • 2 studies processed
P/RResults
LD50 2 000 mg/kg bw (rabbit) [2]
M/CInterpretations of results
Not classified [2]

dermal
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Inhalation route:
No adverse effect observed LC50 5 610 mg/m³
Dermal route:
No adverse effect observed LD50 2 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 209 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 116 90
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 90 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1 1
Supporting study 44 43
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 86 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study 42 41
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study 5 4
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 44 studies submitted
  • 2 studies processed
P/RResults
NOAEC (rat): 9.84 - 20 mg/L air [3]

Study data: inhalation
Studies with data
Key study 3 1
Supporting study 19 21
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 102 studies submitted
  • 8 studies processed
P/RResults
NOAEL (rat): 375 - 3 750 mg/kg bw/day [2]
NOEL (rabbit): 200 - 2 000 mg/kg bw/day [14]

Study data: dermal
Studies with data
Key study 9 1
Supporting study 43 49
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route - systemic effects:
No adverse effect observed NOAEC 1 402 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 42 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 2 2
Supporting study 19 19
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 28 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 2 1
Supporting study 12 13
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 24 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 2
Supporting study 12 9
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Inhalation route:
No adverse effect observed NOAEC 9 869 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 17 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1 2
Supporting study 7 6
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 2 summaries submitted
  • 1 summary processed
Effect on fertility
Inhalation route:
No adverse effect observed NOAEC 20 000 mg/m³ (chronic, rat)
Effect on developmental toxicity
Dermal route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subchronic, rat)
Inhalation route:
No adverse effect observed NOAEC 23 900 mg/m³ (subchronic, rat)

Neurotoxicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 2 summaries submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant