Brief Profile

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Please be aware that the REACH registration parts of this Brief Profile are no longer maintained; they remain frozen as of 19th May 2023. All other data parts (substance identity, C&L, key regulatory lists etc. are up to date).

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
232-433-8
CAS no.:
8028-48-6
Index number:
Molecular formula:
SMILES:
InChI:
Type of substance:
UVCB
Origin:
Other
Registered compositions:
83
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the classification provided by companies to ECHA in REACH registrations this substance may be fatal if swallowed and enters airways, is toxic to aquatic life with long lasting effects, is a flammable liquid and vapour, causes skin irritation and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance is very toxic to aquatic life with long lasting effects, is very toxic to aquatic life and is a highly flammable liquid and vapour.

Breakdown of all 3560 C&L notifications submitted to ECHA

Skin Irrit. 2 H315
Asp. Tox. 1 H304
Skin Sens. 1 H317
Flam. Liq. 3 H226
Aquatic Chronic 1 H410
Aquatic Acute 1 H400
Flam. Liq. 2 H225
Aquatic Chronic 2 H411
Eye Irrit. 2 H319
STOT SE 3 H335
Aquatic Chronic 3 H412
Not Classified
Skin Sens. 1A H317
Skin Sens. 1B H317
Flam. Liq. 1 H224
https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).
  • PBT
There is no overall agreement among data submitters, but a minority indicate they consider this substance as Persistent, Bioaccumulative and Toxic (1.14% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 82 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Seveso Annex I:
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: repelling or attracting pests.

This substance is used in the following products: air care products, cosmetics and personal care products, washing & cleaning products, polishes and waxes, perfumes and fragrances, adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, non-metal-surface treatment products, laboratory chemicals and lubricants and greases.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles and transfer of chemicals.

Release to the environment of this substance can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: leather (e.g. gloves, shoes, purses, furniture), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), metal (e.g. cutlery, pots, toys, jewellery), rubber (e.g. tyres, shoes, toys), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).

This substance is used in the following products: perfumes and fragrances, polishes and waxes and washing & cleaning products.

ECHA has no public registered data on the types of manufacture using this substance.

This substance is used in the following activities or processes at workplace: transfer of chemicals, non-industrial spraying, roller or brushing applications, closed, continuous processes with occasional controlled exposure, treatment of articles by dipping and pouring and batch processing in synthesis or formulation with opportunity for exposure.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance is used in the following products: perfumes and fragrances, coating products and inks and toners.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, laboratory work, closed, continuous processes with occasional controlled exposure, mixing in open batch processes, transfer of substance into small containers, batch processing in synthesis or formulation with opportunity for exposure and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: coating products, perfumes and fragrances and lubricants and greases.

This substance is used in the following areas: building & construction work. This substance is used for the manufacture of: chemicals and machinery and vehicles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, industrial spraying, treatment of articles by dipping and pouring, roller or brushing applications, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, mixing in open batch processes, hand mixing with intimate contact only with personal protective equipment available, batch processing in synthesis or formulation with opportunity for exposure, transfer of substance into small containers, production of mixtures or articles by tabletting, compression, extrusion or pelletisation and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites and in the production of articles.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, transfer of chemicals, closed, continuous processes with occasional controlled exposure, laboratory work and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: keep away from heat, sparks, open flames and/or hot surfaces – No smoking; avoid release to the environment; use explosion-proof equipment (electrical/ventilating/lighting/etc.); do not get in eyes, on skin, or on clothing; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If swallowed: immediately call a poison center or doctor/physician. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. Do not induce vomiting.

Storage statements

Store this substance locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • Agrumaria Corleone SpA, via Salvatore Corleone 12 I-90124 Palermo Italy
  • Agrumi Gel snc, Contrada Girotta 98051 Barcellona P.G. Messina Italy
  • ASTIER-DEMAREST S.A., 60, route de la Paoute 06130 GRASSE France
  • Blue Frog Scientific EURL EU OR8, 967 Route de la Plaine La Plaine 26400 Chabrillan France
  • C.S.B. GmbH, Dujardinstr. 5 47829 Krefeld Germany
  • Campisi Citrus S.r.l., Via Elorina 184 96100 Siracusa Italy
  • Capua 1880 S.r.l., Zona Industriale 89052 Campo Calabro Reggio Calabria Italy
  • CILIONE S.r.l., via S. Antonio Arangea 89132 Reggio Calabria Italy
  • CITRICOS DEL ANDEVALO S.A., Camino de Lepe, S/N 21540 Huelva Spain
  • CITRICOS Y REFRESCANTES SAU, Emilio Donat 14 46740 Carcaixent Valencia Spain
  • CITROFLOR S.R.L., Contrada Vivo snc 89030 Condofuri Marina RC-CALABRIA Italy
  • CITROMIL, S.L., Carretera de Abanilla, Km 1.6 30140 Santomera Murcia Spain
  • Claus Nitsche & Sohn GmbH, Billbrookdeich 122 22113 Hamburg Germany
  • CO-RO A/S, Holmensvej 11 3600 Frederikssund Denmark
  • COMMERCIALE A DUE SRL, via Centonze n. 82 98123 Messina Italy
  • Continental Juice BV, Ijselstraat 25 3029 BM Rotterdam Netherlands
  • DALLANT, Carretera Laureà Miró 392 088980 ST.FELIU DE LLOBREGAT - BARCELONA Spain
  • De Monchy Aromatics BV, Overwegwachter 4 3034KG Rotterdam Netherlands
  • DIEGO VISALLI SRL UNIPERSONALE, Via Pallica n°50 89063 Melito di Porto Salvo (Reggio Calabria) Italy
  • doTERRA Europe Marketing, GmbH, Konrad-Zuse-Platz 4 81829 München Germany
  • Duellberg Konzentra GmbH & Co. KG, Obenhauptstr.3 22335 Hamburg Hamburg Germany
  • Döhler GmbH, Riedstraße 7-9 64295 Darmstadt Hessen Germany
  • Döhler GmbH, Riedstraße 64295 Darmstadt Germany
  • ECSA ITALIA SRL con Unico Socio, Via Lav. Autobianchi, 1 I-20832 Desio (MB) Lombardia Italy
  • elixens france SAS, Ecosite du Val de Drôme 428 rue Brunelle 26400 EURRE France
  • Erich Ziegler GmbH, Am Weiher 133 91347 Aufsess Germany
  • ERNESTO VENTOS, S.A., Carretera Reial 120B 08960 Sant Just Desvern Spain
  • Eurofood srl, piazza San Giuseppe 13 98071 Capo d'Orlando Sicilia Italy
  • F.D.Copeland & Sons (Europe) Limited, 38 Upper Mount street D02 PR89 Dublin Ireland
  • F.lli Branca SpA, Via Maceo,7 98050 Terme Vigliatore (ME) Italy
  • FIRMENICH GRASSE SAS OR 1, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • FIRMENICH GRASSE SAS OR 7, Parc Industriel Le Bois de Grasse 06130 Grasse France
  • FIRMENICH GRASSE SAS OR 8, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • FIRMENICH GRASSE SAS OR6, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • Frey + Lau GmbH, Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany
  • Fruit Tech Natural, Ctra Madrid Cartagena Km 383 30100 Murcia Spain
  • Gioia Succhi S.r.l., Prima Zona Industriale 89026 San Ferdinando RC Italy
  • Giuseppe Sciotto, Piazza San Giuseppe 13, 98070 Capo D'orlando c/da Malvicino 98071 Messina ME Italy
  • Givaudan France SAS - OR1, 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France
  • Givaudan France SAS - OR14, 55, Rue de la voie des Bans 95102 Argenteuil Cedex France
  • Givaudan France SAS - OR2, 55, Rue de la voie des Bans 95102 Argenteuil Cedex France
  • Global Essence Europe B.V, P.O. Box 67 ZH 4254 Sleeuwuk Netherlands
  • GOLGEMMA SA, route de FA 11260 ESPERAZA Languedoc Roussillon France
  • H. REYNAUD & FILS, La Cheminade 26570 MONTBRUN LES BAINS France
  • IFF Benicarlo, S.L., Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain
  • INDULLEIDA, Ctra N-230 km 12 25125 Alguaire Spain
  • International Flavors & Fragrances I.F.F. (Nederland) B.V., Liebergerweg 72-98 1221 JT Hilversum Netherlands
  • J C Buck Europe S.L.U. , Guillem de Muntanyans 139-149 08223 Terrassa Barcelona Spain
  • Johann Voegele KG, Bahnhofstrasse 143 74348 Lauffen Baden-Württemberg Germany
  • l'italiana aromi srl, lombardia 24 20841 carate brianza (mi) Italy
  • LLUCH ESSENCE, S.L.U., Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain
  • Lucta S.A., Carrer de Can Parellada, 28 08170 Montornès del Vallès Barcelona Spain
  • MCI Miritz Citrus GmbH & Co. KG, Citrusstraße 3 37318 Kirchgandern Germany
  • Miguel Parra e Hijos, S.A., Ctra. Abanilla, Km.1 30140 Santomera Murcia Spain
  • Misitano & Stracuzzi S.p.A., Via Ghibellina, 64 98122 Messina Italy
  • Moellhausen spa, Viale delle industrie 95 20040 Cambiago Italy
  • Paul Kaders GmbH, Eschelsweg 27 22767 Hamburg Germany
  • Pranarôm International sa, avenue des Artisans 37 7822 Ghislenghien Hainaut Belgium
  • PRODARESS, P.A. du Pilon, Lot N° 3 06460 SAINT VALLIER DE THIEY France
  • QUIMDIS SAS, 71, rue Anatole France 92532 Levallois-Perret France
  • Ramboll Belgium bvba, 46 Meersbloem-Melden 9700 Oudenaarde Belgium
  • RIVERBEND ESPAÑA, S.L., Crta. ABANILLA Km. 1.5 30140 SANTOMERA MURCIA Spain
  • Robertet, 37 Avenue Sidi Brahim 06130 Grasse France
  • ROBERTET BIO, les marcelons 26340 Vercheny France
  • SAT 1596 NUFRI, Carretera de Palau Km 1 25230 Mollerussa Lérida Spain
  • Sensient Technologies Europe GmbH, Geesthachter Straße 103 21502 Geesthacht Germany
  • SIMONE GATTO srl, C.DA S. BIAGIO 98045 SAN PIER NICETO MESSINA Italy
  • Sunprod Srl, Via Sebastiano Catania 284 95123 Catania Italy
  • Symrise AG, Mühlenfeldstraße 1 37603 Holzminden Germany
  • Symrise Granada, S.A.U., Crta. Armilla Km 2,5 18100 Armilla Granada Spain
  • TER Chemicals GmbH & Co. KG, Börsenbrücke 2 20457 Hamburg Germany
  • TIGI Haircare GmbH, Postfach 700331 70573 Stuttgart Germany
  • Tilley GmbH, Ulmenstraße. 37-39 60325 Frankfurt Germany
  • ULTRA INTERNATIONAL B.V., Malledijk 3H, 3208 LA Spijkenisse NETHERLANDS Netherlands
  • Univar Solutions B.V., Schouwburgplein 30-34 NL-3012 CL Rotterdam Netherlands
  • V. MANE FILS , 620 route de Grasse 06620 Le Bar sur Loup France
  • Veolia Water Technologies & Solutions Belgium BVBA, Toekomstlaan 54 2200 Herentals Belgium
  • Veolia WTS France, Immeuble L'Aquarène 1 place Montgolfier 94417 SAINT-MAURICE CEDEX France
  • VIDARA LIFE INGREDIENTS, S.A.U., Alta Ribagorza, 6-8 08820 El Prat de Llobregat Barcelona Spain
  • Weissmeer Baltische Import-Export GmbH, Colonnaden 51 20354 Hamburg Germany
  • Young Living Europe B.V., Peizerweg 97 9727AJ Groningen Netherlands
  • ZUMOS VALENCIANOS DEL MEDITERRÁNEO S.A., C/ del Pollancar s.n. P.I.Parc Sagunt I 46520 Sagunto Valencia Spain
  • Augustus Oils Ltd, Augustus House Mill Lane GU34 2QG Alton Hampshire United Kingdom
  • Elixens UK Ltd, No 1 Essence House, Crabtree Road Thorpe Industrial Park TW20 8RN Egham Surrey United Kingdom
  • FIRMENICH GRASSE SAS OR 3, Parc Industriel Les Bois de Grasse 06130 Grasse France
  • Heinrich Ihden GmbH, Grosse Bleichen 21 20354 Hamburg Germany
  • PFW Aroma Ingredients B.V., Veemweg 29-31 3771 MT Barneveld Gelderland Netherlands

Substance names and other identifiers

Citrus aurantium dulcis flower extract
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus sinensis, Rutaceae.
Cosmetic Products Regulation, Annex III - Restricted Substances
Citrus Aurantium dulcis peel oil expressed
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus sinensis, Rutaceae.
Annex II, Sec III - Allergenic Fragrances Banned/Restricted in Toys
Citrus aurantium dulcis peel oil
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus sinensis, Rutaceae.
Cosmetic Products Regulation, Annex III - Restricted Substances
Citrus sinensis peel oil expressed
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus sinensis, Rutaceae.
Annex II, Sec III - Allergenic Fragrances Banned/Restricted in Toys
Orange extract
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus sinensis, Rutaceae.
Annex of Approved Active Substances for Plant Protection Products
Orange oil
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus sinensis, Rutaceae.
Statistics on Pesticides Regulation - Annex III Harmonized C&L
Orange, sweet, ext.
EC Inventory, Biocidal active substances
Orange, sweet, ext.
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Citrus sinensis, Rutaceae.
Biocidal active substances, REACH pre-registration
apelsin, magus, ekstrakt (et)
Biocidal active substances
apelsin, söt, extrakt (sv)
Biocidal active substances
Appelsiini, makea, uute (fi)
Biocidal active substances
Appelsin, sød, ekstrakt (da)
Biocidal active substances
appelsin, søt, ekst. (no)
Biocidal active substances
arancio, dolce, estratto (it)
Biocidal active substances
ekstrakt naranče, slatki (hr)
Biocidal active substances
Estratt tal-larinġ, ħelu. (mt)
Biocidal active substances
Extract de portocale dulci (ro)
Biocidal active substances
laranja doce, extrato (pt)
Biocidal active substances
Narancs, édes, kivonat (hu)
Biocidal active substances
naranja, dulce, ext. (es)
Biocidal active substances
orange, douce, ext. (fr)
Biocidal active substances
Orange, süß, Ext. (de)
Biocidal active substances
pomaranča, sladka, ekstrakt (sl)
Biocidal active substances
pomarańcza, słodka, wyciąg (pl)
Biocidal active substances
pomeranč, sladký, výtažek (cs)
Biocidal active substances
saldais apelsīns, ekstrakts (lv)
Biocidal active substances
Saldžiųjų apelsinų ekstraktas (lt)
Biocidal active substances
sinaasappel, zoet, ext. (nl)
Biocidal active substances
sladký pomarančový extrakt (sk)
Biocidal active substances
Γλυκά πορτοκάλια, εκχύλισμα (el)
Biocidal active substances
портокал, сладък, екстр. (bg)
Biocidal active substances
(2E,6E)-2,6-dimethyl-10-methylidenedodeca-2,6,11-trienal; (2E,6E,9E)-2,6,10-trimethyldodeca-2,6,9,11-tetraenal; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; 3,7-dimethylocta-1,6-dien-3-ol; 7-methyl-3-methylideneocta-1,6-diene; octanal
Biocidal active substances, Registration dossier, Other
(2Z,6E)-2,6-dimethyl-10-methylidenedodeca-2,6,11-trienal
Other
(R)-4-isopropenyl-1-methylcyclohexene
C&L Inventory
1,8(9)-p-menthadiene
C&L Inventory
1-methyl-4-(1-methylethenyl)-cyclohexene
C&L Inventory
2,6-dimethyl-10-methylidenedodeca-2,6,11-trienal
C&L Inventory
2E,6E)-2,6-dimethyl-10-methylidenedodeca-2,6,11-trienal; (2E,6E,9E)-2,6,10-trimethyldodeca-2,6,9,11-tetraenal; (4R)-1-methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; 3,7-dimethylocta-1,6-dien-3-ol; 7-methyl-3-methylideneocta-1,6-diene; octanal
C&L Inventory
Citrus Aurantium Dulcis Flower Oil
C&L Inventory
Citrus sinensis (L.) Osbeck (Rutaceae)
C&L Inventory
Citrus sinensis ext
C&L Inventory
Citrus sinensis ext
Registration dossier
citrus sinensis extract
C&L Inventory
Citrus sinensis L.
C&L Inventory
citrus sinensis l. osbeck peel oil cold pressed
C&L Inventory
Citrus sinensis oil
C&L Inventory
Citrus Sinensis Peel oil expressed
C&L Inventory
Citrus sinensis, ext.
C&L Inventory
d-Limonene
C&L Inventory
Essential oil extract of Citrus sinensis (Rutaceae) peel
C&L Inventory
Essential oil of orange obtained from the peel of Citrus sinensis (Rutaceae) by expression and/or distillation, including cold pressed, distilled, terpenes and essence qualities
C&L Inventory, Registration dossier
Essential oil of orange obtained from the peel of Citrus sinensis (Rutaceae) by expression and/or distillation, including cold pressed, distilled, terpenes and essence qualities
Registration dossier
Essential oil of orange obtained from the peel of Citrus sinensis (Rutaceae) by expression and/or distillation, including cold pressed, distilled, terpenes and essence qualities_excluding manufacturing and refinement.Orange Oil
Registration dossier
Essential oil of orange obtained from the peel ofCitrus sinensis (Rutaceae) by expression and/ordistillation, including cold pressed, distilled,terpenes and essence qualities
Registration dossier
Extract, orange, sweet
C&L Inventory
HE Orange
C&L Inventory
Huile essentielle d'Orange douce
C&L Inventory
NOT APPLICABLE
C&L Inventory
Not available; Orange oil
C&L Inventory
orange 10X
C&L Inventory
ORANGE BLOSSOM EXTRACT
C&L Inventory
Orange Essential Oil
Registration dossier
Orange ext.
C&L Inventory
ORANGE OIL
C&L Inventory, Registration dossier
Orange Oil
C&L Inventory, Registration dossier
Orange Oil Sweet
C&L Inventory
orange oil sweet
Registration dossier
Orange oil sweet extract
C&L Inventory
ORANGE OIL, ORANGE OIL FOLDED, ORANGE OIL CP, ORANGE OIL DECOLOURISED, ORANGE OIL MID SEASON, ORANGE OIL VALENCIA, ORANGE TERPENES
Registration dossier
Orange oil, Orange terpenes, Orange sweet extr.
Registration dossier
Orange Oil, sweet
C&L Inventory
Orange oils
C&L Inventory
Orange sweet Essential Oil
C&L Inventory
Orange Sweet Ext
C&L Inventory
Orange Sweet Oil
C&L Inventory
Orange sweet oil
Registration dossier
Orange terpene
Registration dossier
Orange Terpener
C&L Inventory
Orange Terpenes
C&L Inventory
Orange, citrus sinensis, ext
C&L Inventory
Orange, Citrus sinensis, ext
Registration dossier
Orange, Citrus sinensis, ext.
Registration dossier
Orange, sweet
C&L Inventory
Orange, sweet, ect:
C&L Inventory
Orange, sweet, essential oil
C&L Inventory
Orange, sweet, ext
C&L Inventory, Registration dossier
ORANGE, SWEET, EXT.
C&L Inventory, Registration dossier
Orange, Sweet, Ext.
C&L Inventory, Registration dossier
Orange, Sweet, ext. EC 232-433-8
C&L Inventory
Orange, sweet, ext. Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, o
C&L Inventory
Orange, sweet, extr.
C&L Inventory
Orange, sweet, extract - Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from citrus sinensis, rutaceae.
C&L Inventory
Orange, sweet, oil
C&L Inventory
Orangenöl
C&L Inventory
Orangenöl süss
C&L Inventory
Reaction mass of citral and (S)-p-mentha-1,8-diene
C&L Inventory
Sweet Orange Essential Oil
C&L Inventory
Sweet Orange oil
Registration dossier
ARANCIO DOLCE O.E.
Registration dossier
ARANCIO ROSSO O.E.
Registration dossier
BLOOD ORANGE OIL
Registration dossier
BLOOD ORANGE OIL 10-FOLD OWN DIST
Registration dossier
BLOOD ORANGE OIL ITALY (ORGANIC BIO)
Registration dossier
BLOOD ORANGE OIL SICIL
Registration dossier
CITRUS DULCIS
C&L Inventory
CITRUS DULCIS (INCI)
C&L Inventory
Citrus Liquid Extract; in Glycerin / Wasser; 50% Active Matter; active substance
C&L Inventory
CITRUS TERPENES
Registration dossier
CITRUS TERPENES Citrusterpene D'Limonene It. Orange Oil It. Orange oil Decolorized OILPHASE Oils, orange, sweet Oils, orange, sweet, psoralen-free Oils, orange, sweet, terpene-free Oils, orange-juice Oils, orange-juice, Citrus sinensis Orage Oil Guinea Orange 10x Orange 5x Orange Colourless Orange Essence Oil Orange Essence Oil Braz Orange essential oil Orange Folded Orange Oil Orange Oil 1 fold Orange oil 10-fold Orange oil 5-fold Orange oil 5fold Orange Oil 5X Orange Oil Braz. 3X Top Dist. Orange Oil Brazil ORANGE OIL C.P BRAZILLIAN Orange Oil Calif. Cold Pressed Orange Oil california distilled Orange Oil California key brand Orange Oil CO2 5X ORANGE OIL COLD PRESSED Orange Oil Colourless Dmc Orange Oil Colourless N.S. Orange oil concentrate Orange oil concentrate decolourized Orange Oil Decolorised 15x pure Orange Oil Decolorized Orange Oil Decolourised Orange oil decolourized Orange Oil Distilled Orange oil expressed ORANGE OIL FLORIDA Orange Oil Florida Valencia Orange Oil Florida Valencia Type Orange Oil Floride 5-Fold ORANGE OIL FOLDED Orange Oil Guinea Orange Oil Ital. Sweet Orange Oil Ital. Sweet Decol. Orange Oil MC50 Nat. Orange Oil Mid. Orange oil Mid. 10X Orange Oil P 10X Orange Oil Phase Orange Oil Shamouti Orange Oil Shamouti TPA ORANGE OIL SPANISH Orange Oil Sweet Orange Oil Sweet Italian Tarocco Orange Oil sweet Valencia; Orange Oil 1-Fold; Orange Terpenes; Orange Juice Oils; Orange Essence Oils folded; Orange Oil folded; Orange Oil 10-Fold; Orange Oil 8-Fold; Orange Oil terpenfree; Orange Oil Terpeneless Orange Oil Terpeneless Natural Orange Oil Terpenes ORANGE OIL TERPENLESS Orange Oil Type Israel/Sham. 10X ORANGE OIL VALENCIA Orange Oil, Sweet orange oil, sweet (high con
Registration dossier
Citrusterpene
Registration dossier
Citrusterpene D
Registration dossier
D'Limonene
Registration dossier
He.Ex.Orangenfrucht COS-241/803A; in Propylenglykol (PG) / PEG-40 / HYDROGENATED CASTOR OIL
C&L Inventory
Herb.-Ext. Orangenschale COS-241/356-F; in Propylenglykol (PG) / Wasser
C&L Inventory
Herbasol Extr. Orangenblüten in 80% PG unkon., entf. (COS 241/651 G); in Propylenglykol (PG) / Wasser
C&L Inventory
Herbasol Extract Orange Flowers COS-241/651- in 80% PG; in Propylenglycol / Water / Sorbitol
C&L Inventory
Herbasol Extract Orange Flowers COS-241/651-G in 80% PG; in Propylenglycol / Water / Sorbitol
C&L Inventory
Herbasol Extrakt Blutorange PG unkons System 3; in Propylenglykol (PG) / H2O
C&L Inventory
Herbasol Extrakt Blutorange unkons 80%, PG (System3); in Propylenglykol (PG) / Wasser
C&L Inventory
Herbasol Extrakt Orangenfrucht (COS-241/803-A); in Propylenglykol (PG) / PEG-40 / HYDROGENATED CASTOR OIL
C&L Inventory
Herbasol Extrakt Orangenfrucht 241/803-A; in Propylenglykol (PG) / PEG-40 / HYDROGENATED CASTOR OIL
C&L Inventory
Herbasol Extrakt Orangenschale süss (COS 241/356 F); in Propylenglykol (PG) / Wasser
C&L Inventory
Huile Essentielle d'Orange
C&L Inventory
It. Orange Oil
Registration dossier
It. Orange oil Decolorized
Registration dossier
Italian Orange Oil Tarocco 10X L70
C&L Inventory
Italian Orange Oil Tarocco 20X L45
C&L Inventory
Limonene It.
Registration dossier
Mandora oil
C&L Inventory
Oange oil CO2 5X
Registration dossier
OILPHASE
Registration dossier
Oils, orange, sweet
Registration dossier
Oils, orange, sweet, psoralen-free
Registration dossier
Oils, Orange, sweet, terpene-free
Registration dossier
Oils, orange-juice
Registration dossier
Oils, orange-juice, Citrus sinensis
Registration dossier
Orage Oil Guinea
Registration dossier
Orange 10x
Registration dossier
Orange 5x
Registration dossier
Orange Colourless
Registration dossier
ORANGE DOUCE ITALIE DEFUROCOUMARINIZEE H.E.
Registration dossier
ORANGE DOUCE ITALIE H.E.
Registration dossier
Orange Essence Oil
Registration dossier
Orange Essence Oil Braz
Registration dossier
Orange essential oil
Registration dossier
ORANGE EXTRACT
C&L Inventory
ORANGE FLOWER EXTRACT
C&L Inventory
ORANGE FLOWER OIL
C&L Inventory
ORANGE FLOWER WATER
C&L Inventory
Orange Folded
Registration dossier
ORANGE OIL
C&L Inventory, Registration dossier
Orange Oil 1 fold
Registration dossier
Orange Oil 1-fold
Registration dossier
Orange oil 10-fold
Registration dossier
ORANGE OIL 10X
Registration dossier
ORANGE OIL 5 FOLD
Registration dossier
Orange oil 5-fold
Registration dossier
Orange oil 5fold
Registration dossier
Orange Oil 5X
Registration dossier
ORANGE OIL 7-FOLD OWN DIST
Registration dossier
Orange Oil Braz. 3X Top Dist.
Registration dossier
ORANGE OIL BRAZIL
Registration dossier
ORANGE OIL C.P BRAZILIAN
Registration dossier
ORANGE OIL CALABIRAN
Registration dossier
Orange Oil Calif. Cold Pressed
Registration dossier
Orange Oil California distilled
Registration dossier
Orange Oil California key brand
Registration dossier
Orange Oil CO2 5X
Registration dossier
ORANGE OIL COLD PRESSED
Registration dossier
ORANGE OIL COLD PRESSED 1-FOLD
Registration dossier
ORANGE OIL COLD PRESSED 10 FOLD
Registration dossier
ORANGE OIL COLORLESS
Registration dossier
Orange Oil Colourless Dmc
Registration dossier
Orange Oil Colourless N.S.
Registration dossier
Orange oil concentrate
Registration dossier
Orange oil concentrate decolourized
Registration dossier
Orange Oil Decolorised 15x pure
Registration dossier
Orange Oil Decolorized
Registration dossier
Orange Oil Decolourised
Registration dossier
Orange oil decolourized
Registration dossier
Orange Oil Distilled
Registration dossier
ORANGE OIL DM
Registration dossier
Orange oil expressed
Registration dossier
Orange Oil F100
C&L Inventory
ORANGE OIL FLORIDA
Registration dossier
Orange Oil Florida Valencia
Registration dossier
Orange Oil Florida Valencia Type
Registration dossier
Orange Oil Floride 5-Fold
Registration dossier
Orange Oil Guinea
Registration dossier
Orange Oil It.
Registration dossier
Orange Oil Ital. Sweet
Registration dossier
Orange Oil Ital. Sweet Decol.
Registration dossier
ORANGE OIL ITALIAN
Registration dossier
ORANGE OIL ITALY
Registration dossier
Orange Oil MC50 Nat.
Registration dossier
Orange Oil Mid.
Registration dossier
Orange oil Mid. 10X
Registration dossier
ORANGE OIL MIDSEASON FLARIDA USA
Registration dossier
Orange Oil P 10X
Registration dossier
Orange Oil Phase
Registration dossier
Orange Oil Shamouti
Registration dossier
Orange Oil Shamouti TPA
Registration dossier
ORANGE OIL SICILIAN
Registration dossier
ORANGE OIL SICILY
Registration dossier
Orange Oil Sweet
Registration dossier
Orange Oil Sweet Italian Tarocco
Registration dossier
ORANGE OIL SWEET ITALY
Registration dossier
ORANGE OIL SWEET ITALY (ORGANIC BIO)
Registration dossier
Orange Oil sweet Valencia; Orange Oil 1-Fold; Orange Terpenes; Orange Juice Oils; Orange Essence Oils folded; Orange Oil folded; Orange Oil 10-Fold; Orange Oil 8-Fold; Orange Oil terpenfree;
Registration dossier
Orange Oil Terpeneless
Registration dossier
Orange Oil Terpeneless Natural
Registration dossier
Orange Oil Terpenes
Registration dossier
ORANGE OIL TYPE CALIFORNIA
Registration dossier
Orange Oil Type Israel/Sham. 10X
Registration dossier
Orange Oil Valencia
Registration dossier
Orange Oil, Sweet
Registration dossier
orange oil, sweet (high concentration levels of D-Limonene; cas 5989-27-5; orange oil 5 fold; orange oil 10 fold; orange oil 20 fold; orange oil 40 fold; orange oil 7/8 fold; orange oil phase; orange terpenes; distilled orange oil
Registration dossier
ORANGE PEEL EXTRACT
C&L Inventory
Orange Peel Oil, sweet
C&L Inventory
ORANGE PEEL WAX
C&L Inventory
ORANGE PEEL WAX (INCI)
C&L Inventory
Orange Phase Oil
Registration dossier
ORANGE SANGUINE ITALIE H.E.
Registration dossier
Orange Sweet Psoralen Free
Registration dossier
Orange Sweet Terpene Free
Registration dossier
Orange Tarocco
Registration dossier
Orange Tarocco 5x
Registration dossier
Orange Tarocco Decolorized
Registration dossier
Orange Tarocco Decolourised
Registration dossier
Orange Tarocco Hi-conc. Extract low allergens
C&L Inventory
Orange terpene (D-Limonene)
Registration dossier
ORANGE TERPENES
Registration dossier
Orange Terpenes Distilled
Registration dossier
Orange, sweet, ext.
C&L Inventory
Orange, sweet, Valencia, ext.
Registration dossier
Orangen oil MC 10 (9/026163)
C&L Inventory
Orangenfrischsafnoel Brasilianisch Nat
Registration dossier
Orangenoel 7-Fach Natuerlich
Registration dossier
Orangenoel P36 Valencia Nat. Terpene
Registration dossier
Orangenoel Rueckstand
Registration dossier
Orangenschalenöl
Registration dossier
Orangenterpene
Registration dossier
Orangenöl
Registration dossier
Qrangenöl
Registration dossier
SWEET ORANGE OIL
Registration dossier
SWEET ORANGE OIL CALABRIAN
Registration dossier
Sweet Orange Oil Cold Pressed
Registration dossier
SWEET ORANGE OIL COLD PRESSED 1-FOLD
Registration dossier
SWEET ORANGE OIL ITALIAN
Registration dossier
SWEET ORANGE OIL ITALY
Registration dossier
SWEET ORANGE OIL SICILIAN
Registration dossier
SWEET ORANGE OIL SICILY
Registration dossier
SWEET ORANGE OIL TERPENES
Registration dossier
Sweet orange peel tincture
C&L Inventory
Terpenes and Terpenoids, orange-oil; Terpenes and Terpenoids, sweet orange-oil
Registration dossier
orangenöl
REACH pre-registration
68647-72-3
CAS number
C&L Inventory
8028-48-6
CAS number
EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other, Cosmetic Products Regulation, Annex III - Restricted Substances, Statistics on Pesticides Regulation - Annex III Harmonized C&L, Annex of Approved Active Substances for Plant Protection Products, Annex II, Sec III - Allergenic Fragrances Banned/Restricted in Toys

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Natural substance (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 1 study submitted
  • 1 study processed
R Melting / freezing point
-25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Boiling point

Study results
  • 1 study submitted
  • 1 study processed
R Boiling point
160 °C @ 102.6 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
160 °C

Density

Study results
  • 1 study submitted
  • 1 study processed
R Density
0.846 g/cm³ @ 20 °C [1]
R Relative density
0.847 @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.847

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
1.864 hPa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
1.864 hPa @ 25 °C

Partition coefficient

Study results
  • 2 studies submitted
  • 1 study processed
R Log Pow
2.78 - 4.88 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
4.38

Water solubility

Study results
  • 1 study submitted
  • 1 study processed
R Water solubility (mass/vol.)
3.48 - 1 767.3 mg/L @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Flash point

Study results
  • 1 study submitted
  • 1 study processed
R Flash point
53.4 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 1 study processed
R Autoflammability / self-ignition
235 °C @ 101.22 - 101.65 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
235 °C

Flammability

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Viscosity

Study results
  • 1 study submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
0.99 [1]
R kinematic viscosity (in mm²/s)
1.17 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
0.99 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 6 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other 2
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - L/kg ww
361 L/kg ww

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Henrys law constant (H)

Data not provided by the registrant

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 5.4 µg/L (1)
Intermittent releases (freshwater) 5.77 µg/L (1)
Marine water 540 ng/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 2.1 mg/L (1)
Sediment (freshwater) 1.3 mg/kg sediment dw (1)
Sediment (marine water) 130 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 261 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential to cause toxic effects if accumulated (in higher organisms) via the food chain (1)

Short–term toxicity to fish

Study results
  • 7 studies submitted
  • 1 study processed
P/RResults
LL50 (4 days) 5.65 mg/L [1]
LL10 (4 days) 5.25 mg/L [1]
NOELR (4 days) 4 mg/L [1]
LOELR (4 days) 8 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Short–term toxicity to aquatic invertebrates

Study results
  • 9 studies submitted
  • 1 study processed
P/RResults
EL50 (48 h) 1.1 mg/L [1]
EL50 (24 h) 1.4 mg/L [1]
NOELR (48 h) 480 µg/L [1]
LOELR (48 h) 1 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to aquatic algae and cyanobacteria

Study results
  • 7 studies submitted
  • 2 studies processed
P/RResults
EL50 (72 h) 4.3 - 150 mg/L [4]
NOELR (72 h) 50 mg/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 5
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
4.3 mg/L
EC10 or NOEC for freshwater algae
50 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 31.1 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.89 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: (DNEL) 185.8 µg/cm² sensitisation (skin)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 7.78 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.44 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: (DNEL) 92.9 µg/cm² sensitisation (skin)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.44 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Other [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
dermal
  • 1 study submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rabbit) [1]
M/CInterpretations of results
Other [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 5 000 mg/kg bw
Dermal route:
No adverse effect observed LD50 5 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
No study available

Sensitisation

Study results
Study data: skin
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 11 studies submitted
  • 3 studies processed
P/RResults
NOAEL (rat): 150 - 2 400 mg/kg bw/day [3]
NOAEL (mouse): 500 mg/kg bw/day [1]
NOAEL (dog): 100 mg/kg bw/day [1]
LOAEL (rat): 1 200 mg/kg bw/day [2]
LOAEL (mouse): 1 000 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 2 2
Weight of evidence 3 3
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: inhalation
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No study available

Carcinogenicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: developmental
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence 3 3
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant